Lenalidomide enhances antitumor functions of chimeric antigen receptor modified T cells

Pavel Otáhal, Dana Průková, Vlastimil Král, +5

OncoImmunology

SCIMP, a Transmembrane Adaptor Protein Involved in Major Histocompatibility Complex Class II Signaling

Peter Dráber, Ivana Vonkova, Ondřej Štěpánek, +9

Molecular and Cellular Biology

ImmunologyMolecular BiologyCellular PhysiologySignaling PathwayReceptor Tyrosine Kinase +14

Electroconvulsive shock and lidocaine reveal rapid consolidation of spatial working memory in the water maze.

Véronique D. Bohbot, Pavel Otáhal, Zhaoli Liu, +2

Proceedings of the National Academy of Sciences

Traumatic Brain InjuryNeuropsychologyElectroconvulsive ShockBilateral InactivationExplicit Memory +22

A new approach to CAR T-cell gene engineering and cultivation using piggyBac transposon in the presence of IL-4, IL-7 and IL-21

Pavlína Ptáčková, Jan Musil, Martin Štach, +5

Cytotherapy

XenotransplantationPiggybac TransposonMedicineT-regulatory CellImmunology +7

Inducible secretion of IL-21 augments anti-tumor activity of piggyBac-manufactured chimeric antigen receptor T cells

Martin Štach, Pavlína Ptáčková, Martin Mucha, +3

Cytotherapy

Autoimmune DiseaseInducible SecretionImmunologyImmunologic MechanismAntigen Processing +5

Inefficient Cross-Presentation Limits the CD8+ T Cell Response to a Subdominant Tumor Antigen Epitope

Pavel Otáhal, Sandra C. Hutchinson, Lawrence M. Mylin, +3

The Journal of Immunology

PSTPIP2, a Protein Associated with Autoinflammatory Disease, Interacts with Inhibitory Enzymes SHIP1 and Csk

Ales Drobek, Jarmila Králová, Tereza Skopcova, +6

The Journal of Immunology

A New Type of Membrane Raft-Like Microdomains and Their Possible Involvement in TCR Signaling

Pavel Otáhal, Pavla Angelisová, Matouš Hrdinka, +4

The Journal of Immunology

Proteinlipid InteractionNew TypeMolecular BiologyAnalytical UltracentrifugationCellular Physiology +18

Adjuvant effect of dendritic cells transduced with recombinant vaccinia virus expressing HPV16-E7 is inhibited by co-expression of IL12.

Jana Macková, L Kutinová, Petr Hainz, +5

PubMed

Adjuvant EffectImmunologyImmunotherapyTumor ImmunityE7 Protein +14

Early Immunization Induces Persistent Tumor-Infiltrating CD8+ T Cells against an Immunodominant Epitope and Promotes Lifelong Control of Pancreatic Tumor Progression in SV40 Tumor Antigen Transgenic Mice

Pavel Otáhal, Todd D. Schell, Sandra C. Hutchinson, +2

The Journal of Immunology