Epigenetic regulation of PPARGC1A in human type 2 diabetic islets and effect on insulin secretion

Charlotte Ling, S Del Guerra, R Lupi, +7

Diabetologia

Overexpression of Alpha2A-Adrenergic Receptors Contributes to Type 2 Diabetes

Anders H. Rosengren, Ramūnas Jokubka, Damon Tojjar, +13

Science

GeneticsGenetic EpidemiologyInsulin SignalingMolecular PharmacologyMetabolic Syndrome +14

Safety and Pharmacokinetics of Single and Multiple Ascending Doses of the Novel Oral Human GLP-1 Analogue, Oral Semaglutide, in Healthy Subjects and Subjects with Type 2 Diabetes

Charlotte Granhall, Morten Donsmark, Thalia Marie Blicher, +4

Clinical Pharmacokinetics

Pharmacokinetics, Safety and Tolerability of Oral Semaglutide in Subjects with Renal Impairment

Charlotte Granhall, Flemming L. Søndergaard, Mette S. Thomsen, +1

Clinical Pharmacokinetics

Insulin degludec's ultra-long pharmacokinetic properties observed in adults are retained in children and adolescents with type 1 diabetes

Torben Biester, Sarah Blaesig, K Remus, +7

Pediatric Diabetes

Insulin DegludecUltra-long Pharmacokinetic PropertiesObesityMetabolic SyndromeType 1 +15

High-Resolution Quantitative Trait Locus Analysis Reveals Multiple Diabetes Susceptibility Loci Mapped to Intervals &amp;lt;800 kb in the Species-Conserved<i>Niddm1i</i>of the GK Rat

Charlotte Granhall, Hee-Bok Park, Hossein Fakhrai-Rad, +1

Genetics

Insulin degludec has a two-fold longer half-life and a more consistent pharmacokinetic profile compared with insulin glargine

Tim Heise, Ulrike Hövelmann, Leszek Nosek, +3

Society for Endocrinology BES 2012

Molecular PharmacologyDiabetes ManagementConsistent Pharmacokinetic ProfileInsulin GlargineInsulin Degludec +7

The effect of Lu AG09222 on PACAP38- and VIP-induced vasodilation, heart rate increase, and headache in healthy subjects: an interventional, randomized, double-blind, parallel-group, placebo-controlled study

Nadja Bredo Rasmussen, Christina Deligianni, Casper Emil Christensen, +6

The Journal of Headache and Pain

Separately Inherited Defects in Insulin Exocytosis and β-Cell Glucose Metabolism Contribute to Type 2 Diabetes

Charlotte Granhall, Anders H. Rosengren, Erik Renström, +1

Diabetes

Metabolic DisorderGeneticsInsulin SignalingMetabolic SyndromeInsulin Delivery +14

Rates of metabolism of chlorzoxazone, dextromethorphan, 7-ethoxycoumarin, imipramine, quinidine, testosterone and verapamil by fresh and cryopreserved rat liver slices, and some comparisons with microsomes

Hanna Axelsson, Charlotte Granhall, E. Floby, +3

Toxicology in Vitro

Pharmacological StudyBiochemistryMedicineLiver PhysiologyPhysiology +9