Lucille L’Heureux

Discovery of thiophene-2-carboxylic acids as potent inhibitors of HCV NS5B polymerase and HCV subgenomic RNA replication. Part 2: Tertiary amides

Sanjoy K. Das, Carl Poisson, Marc Courchesne et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 101 citations · Full text

Life Sciences, Medicinal Chemistry, Molecular Biology +17

Discovery of thiophene-2-carboxylic acids as potent inhibitors of HCV NS5B polymerase and HCV subgenomic RNA replication. Part 1: Sulfonamides

Laval Chan, Sanjoy Das, T. Jagadeeswar Reddy et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 76 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

Mechanism of Action and In Vitro Activity of 1′,3′-Dioxolanylpurine Nucleoside Analogues against Sensitive and Drug-Resistant Human Immunodeficiency Virus Type 1 Variants

Zhengxian Gu, Mark A. Wainberg, Nghe Nguyen‐Ba et al. · Antimicrobial Agents and Chemotherapy · 1999 · 69 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14

Identification of <i>N,N</i>-Disubstituted Phenylalanines as a Novel Class of Inhibitors of Hepatitis C NS5B Polymerase

Laval Chan, T. Jagadeeswar Reddy, Mélanie Proulx et al. · Journal of Medicinal Chemistry · 2003 · 68 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16

Docking Ligands into Flexible and Solvated Macromolecules. 2. Development and Application of F<scp>itted</scp> 1.5 to the Virtual Screening of Potential HCV Polymerase Inhibitors

Christopher R. Corbeil, Pablo Englebienne, Constantin G. Yannopoulos et al. · Journal of Chemical Information and Modeling · 2008 · 58 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17