High-Content Screening in hPSC-Neural Progenitors Identifies Drug Candidates that Inhibit Zika Virus Infection in Fetal-like Organoids and Adult Brain

Ting Zhou, Lei Tan, G. Cederquist, +10

Cell stem cell

Fetal-like OrganoidsNeurobiology Of DiseaseNeurogenomicsCerebral OrganoidBrain-immune Interaction +9

Analysis of ACE2 in polarized epithelial cells: surface expression and function as receptor for severe acute respiratory syndrome-associated coronavirus

Xiaofeng Ren, Jörg Glende, Marwan Alfalah, +8

Journal of General Virology

Acute Lung InjuryViral PathogenesisImmunologyPathologyViral Structural Protein +15

Expression cloning of functional receptor used by SARS coronavirus

Peigang Wang, Jian Chen, Aihua Zheng, +15

Biochemical and Biophysical Research Communications

Viral PathogenesisImmunologyVirologyViral Structural ProteinSars Coronavirus +2

Only One Protomer Is Active in the Dimer of SARS 3C-like Proteinase

Hao Chen, Ping Wei, Changkang Huang, +3

Journal of Biological Chemistry

Protein ChemistryProtein AssemblyBiochemistryNatural SciencesProtein X-ray Crystallography +4

MicroRNA MiR-214 Regulates Ovarian Cancer Cell Stemness by Targeting p53/Nanog

Cheng‐Xiong Xu, Meng Xu, Lei Tan, +8

Journal of Biological Chemistry

Cancer BiologyTumor BiologyOvarian CancerCancer Cell BiologyStem Cells +14

An Isogenic Human ESC Platform for Functional Evaluation of Genome-wide-Association-Study-Identified Diabetes Genes and Drug Discovery

Hui Zeng, Min Guo, Ting Zhou, +11

Cell stem cell

BioinformaticsGenome-wide Association StudyFunctional EvaluationTranslational BioinformaticsGenetics +12

Highly infectious SARS-CoV pseudotyped virus reveals the cell tropism and its correlation with receptor expression

Yuchun Nie, Peigang Wang, Xuanling Shi, +13

Biochemical and Biophysical Research Communications

Infectious Sars-covViral PathogenesisImmunologyVirologyVirus-host Interaction +5

The N-terminal octapeptide acts as a dimerization inhibitor of SARS coronavirus 3C-like proteinase

Ping Wei, Keqiang Fan, Hao Chen, +8

Biochemical and Biophysical Research Communications

Viral ReplicationBiochemistryNatural SciencesAntiviral Drug DevelopmentMolecular Biology +8

GABAergic Excitotoxicity Injury of the Immature Hippocampal Pyramidal Neurons' Exposure to Isoflurane

Yilin Zhao, Qiang Xiang, Qixin Shi, +5

Anesthesia & Analgesia

Antigenicity and Immunogenicity of Differentially Glycosylated Hepatitis C Virus E2 Envelope Proteins Expressed in Mammalian and Insect Cells

Richard A. Urbanowicz, Ruixue Wang, John E. Schiel, +12

Journal of Virology