Ganfeng Wang

Discovery of the 3-Imino-1,2,4-thiadiazinane 1,1-Dioxide Derivative Verubecestat (MK-8931)–A β-Site Amyloid Precursor Protein Cleaving Enzyme 1 Inhibitor for the Treatment of Alzheimer’s Disease

Jack D. Scott, Sarah W. Li, Andrew P. J. Brunskill et al. · Journal of Medicinal Chemistry · 2016 · 161 citations · Full text

Neurochemical Biomarkers, Peptide Science, Enzyme 1 +19

Inhibition of O-GlcNAcase leads to elevation of O-GlcNAc tau and reduction of tauopathy and cerebrospinal fluid tau in rTg4510 mice

Nicholas B. Hastings, Xiaohai Wang, Lixin Song et al. · Molecular Neurodegeneration · 2017 · 148 citations · Full text

High-Performance Liquid Chromatography-Atmospheric Pressure Photoionization/Tandem Mass Spectrometric Analysis for Small Molecules in Plasma

Yunsheng Hsieh, Kara Merkle, Ganfeng Wang et al. · Analytical Chemistry · 2003 · 81 citations

Pharmacotherapy, Chemistry, Spectrochemical Analysis +20

A study of common discovery dosing formulation components and their potential for causing time‐dependent matrix effects in high‐performance liquid chromatography tandem mass spectrometry assays

Xiao‐Ying Xu, Mei Hong, Shiyong Wang et al. · Rapid Communications in Mass Spectrometry · 2005 · 61 citations

Apci Mode, Formulation Components, Pharmacological Study +18

Direct Plasma Analysis of Drug Compounds Using Monolithic Column Liquid Chromatography and Tandem Mass Spectrometry

Yunsheng Hsieh, Ganfeng Wang, Yuguang Wang et al. · Analytical Chemistry · 2003 · 55 citations

Plasma Injections, Analytical Instrumentation, Separation Science +19