CD4⁺CD25⁺ regulatory T cells suppress tumor immunity but are sensitive to cyclophosphamide which allows immunotherapy of established tumors to be curative

François Ghiringhelli, Nicolas Larmonier, E. Schmitt, +7

European Journal of Immunology

T-regulatory CellImmunologyImmune RegulationImmunoeditingRegulatory T Cells +18

Tumor cells can escape DNA‐damaging cisplatin through DNA endoreduplication and reversible polyploidy

Pierre‐Emmanuel Puig, Marie‐Noëlle Guilly, André Bouchot, +9

Cell Biology International

Increase of CD4+CD25+ regulatory T cells in the peripheral blood of patients with metastatic carcinoma: a Phase I clinical trial using cyclophosphamide and immunotherapy to eliminate CD4+CD25+ T lymphocytes

Sylvain Audia, Alexandra Nicolas, Dominique Cathelin, +12

Clinical & Experimental Immunology

Administration of Recombinant Soluble Urokinase Receptor Per Se Is Not Sufficient to Induce Podocyte Alterations and Proteinuria in Mice

Dominique Cathelin, Sandrine Placier, Michael Ploug, +6

Journal of the American Society of Nephrology

Podocyte AlterationsRenal PathologyImmunologyRenal InflammationKidney Disease +15

Peroxynitrite-Dependent Killing of Cancer Cells and Presentation of Released Tumor Antigens by Activated Dendritic Cells

Jennifer Fraszczak, Malika Trad, Nona Janikashvili, +11

The Journal of Immunology

Targeting connexin 43 protects against the progression of experimental chronic kidney disease in mice

Ahmed Abed, Julie Toubas, Panagiotis Kavvadas, +7

Kidney International

InflammationCytokineRenal FunctionMedicineKidney Failure +8

Expression of TLR9 in tumor‐infiltrating mononuclear cells enhances angiogenesis and is associated with a worse survival in lung cancer

L. Belmont, Nathalie Rabbe, Martine Antoine, +5

International Journal of Cancer

Innate Immune SystemImmunologyPathologyImmunologic MechanismInnate Immunity +18

Apoptotic, necrotic, or fused tumor cells: An equivalent source of antigen for dendritic cell loading

Nicolas Larmonier, Delphine Mérino, Alexandra Nicolas, +7

APOPTOSIS

Cancer ImmunosurveillanceDendritic CellImmunologyCell DeathPathology +10

Dendritic Cells Trigger Tumor Cell Death by a Nitric Oxide-Dependent Mechanism

Alexandra Nicolas, Dominique Cathelin, Nicolas Larmonier, +6

The Journal of Immunology

The inhibition of TNF-α anti-tumoral properties by blocking antibodies promotes tumor growth in a rat model

Nicolas Larmonier, Dominique Cathelin, Claire B. Larmonier, +11

Experimental Cell Research

Cancer ImmunosurveillanceTumor GrowthTnf-α Anti-tumoral PropertiesImmunologyTumor Immunity +7