B-Cell-Specific Diversion of Glucose Carbon Utilization Reveals a Unique Vulnerability in B Cell Malignancies

Gang Xiao, Lai N. Chan, Lars Klemm, +17

Cell

Hematological MalignancyLymphoid NeoplasiaOncologyMalignant DiseaseMedicine +10

IFITM3 functions as a PIP3 scaffold to amplify PI3K signalling in B cells

Jae Woong Lee, Mark E. Robinson, Ning Ma, +26

Nature

Signal TransductionSignaling PathwayCell RegulationCell InteractionImmunology +8

JAFFAL: detecting fusion genes with long-read transcriptome sequencing

N. Davidson, Ying Chen, Teresa Sadras, +5

Genome biology

Signalling input from divergent pathways subverts B cell transformation

Lai N. Chan, Mark A. Murakami, Mark E. Robinson, +25

Nature

Signal TransductionSignaling PathwayCell TraffickingCellular Regulatory MechanismB Cell Transformation +3

TGF-α and IL-6 plasma levels selectively identify CML patients who fail to achieve an early molecular response or progress in the first year of therapy

Eva Nievergall, John Reynolds, Chung Hoow Kok, +13

Leukemia

CytokineMedicineT-regulatory CellImmunologyHematology +6

Pre-B acute lymphoblastic leukaemia recurrent fusion, EP300-ZNF384, is associated with a distinct gene expression

Barbara J. McClure, Susan L. Heatley, Chung Hoow Kok, +7

British Journal of Cancer

The GM-CSF receptor utilizes β-catenin and Tcf4 to specify macrophage lineage differentiation

Anna Brown, Diana Salerno, Teresa Sadras, +9

Differentiation

Cell LineageSignal TransductionSignaling PathwayMolecular PathwayImmunology +7

Developmental partitioning of SYK and ZAP70 prevents autoimmunity and cancer

Teresa Sadras, M. Martin, Kohei Kume, +27

Molecular Cell

ImmunogeneticsAutoimmune DiseaseImmunologyDevelopmental PartitioningAutoimmunity +4

Differential expression of MUC4, GPR110 and IL2RA defines two groups of CRLF2-rearranged acute lymphoblastic leukemia patients with distinct secondary lesions

Teresa Sadras, Susan L. Heatley, Chung Hoow Kok, +13

Cancer Letters

Hematological MalignancyTumor BiologyDifferential ExpressionMedicineMixed-phenotype Acute Leukemia +7

Interleukin-3-mediated regulation of β-catenin in myeloid transformation and acute myeloid leukemia

Teresa Sadras, Michelle Perugini, Chung Hoow Kok, +10

Journal of Leukocyte Biology