Assael A. Madrigal

Robust single-cell discovery of RNA targets of RNA-binding proteins and ribosomes

Kristopher W. Brannan, Isaac A. Chaim, Ryan J. Marina et al. · Nature Methods · 2021 · 176 citations · Full text

Engineering, Molecular Biology, Rna-binding Proteins +16

Inhibition of YTHDF2 triggers proteotoxic cell death in MYC-driven breast cancer

Jaclyn M. Einstein, Mark Perelis, Isaac A. Chaim et al. · Molecular Cell · 2021 · 175 citations · Full text

Reintroduction of the archaic variant of <i>NOVA1</i> in cortical organoids alters neurodevelopment

Cleber A. Trujillo, Edward S. Rice, Nathan K. Schaefer et al. · Science · 2021 · 135 citations · Full text

Transcriptome–pathology correlation identifies interplay between TDP-43 and the expression of its kinase CK1E in sporadic ALS

Florian Krach, Ranjan Batra, Emily C. Wheeler et al. · Acta Neuropathologica · 2018 · 102 citations · Full text

Neurodegenerative Diseases, Amyotrophic Lateral Sclerosis, Signal Transduction +10

Expansion of the Major Facilitator Superfamily (MFS) to include novel transporters as well as transmembrane-acting enzymes

Steven C Wang, Pauldeen Mikail Davejan, Kevin J. Hendargo et al. · Biochimica et Biophysica Acta (BBA) - Biomembranes · 2020 · 71 citations · Full text

Protein Secretion, Signal Transduction, Biochemistry +11