DDX5 plays essential transcriptional and post-transcriptional roles in the maintenance and function of spermatogonia

Julien M. D. Legrand, Ai-Leen Chan, Hue M. La, +4

Nature Communications

Identification of dynamic undifferentiated cell states within the male germline

Hue M. La, Juho‐Antti Mäkelä, Ai-Leen Chan, +6

Nature Communications

Germline Stem Cell Activity Is Sustained by SALL4-Dependent Silencing of Distinct Tumor Suppressor Genes

Ai-Leen Chan, Hue M. La, Julien M. D. Legrand, +5

Stem Cell Reports

Cep55 overexpression causes male‐specific sterility in mice by suppressing Foxo1 nuclear retention through sustained activation of PI3K/Akt signaling

Debottam Sinha, Murugan Kalimutho, Josephine Bowles, +9

The FASEB Journal

GILZ-dependent modulation of mTORC1 regulates spermatogonial maintenance

Hue M. La, Ai-Leen Chan, Julien M. D. Legrand, +6

Development

The E3-ligase E6AP Represses Breast Cancer Metastasis via Regulation of ECT2-Rho Signaling

Mariam Mansour, Sue Haupt, Ai-Leen Chan, +16

Cancer Research

Breast Cancer MetastasisBreast OncologyBasal Breast CancerRho GtpasesMedicine +12

Restoration of tumor suppression in prostate cancer by targeting the E3 ligase E6AP

Piotr Paul, Dinesh Raghu, Ai-Leen Chan, +14

Oncogene

UrologyGenitourinary CancerMedicineTumor SuppressionTumor Suppressor +6

E6AP promotes prostate cancer by reducing p27 expression

Dinesh Raghu, Piotr Paul, Twishi Gulati, +13

Oncotarget

Tumor BiologyUrologyMedicineCancer Cell BiologyProtein Degradation +10

Distinctive molecular features of regenerative stem cells in the damaged male germline

Hue M. La, Jinyue Liao, Julien M. D. Legrand, +6

Nature Communications

Expression of E6AP and PML predicts for prostate cancer progression and cancer-specific death

Simone Birch, James G. Kench, Elena A. Takano, +9

Annals of Oncology

UrologyOncologyMedicineCell DeathPathology +9