Thomas Lanyon‐Hogg

Dual chemical probes enable quantitative system-wide analysis of protein prenylation and prenylation dynamics

Elisabeth M. Storck, Julia Morales‐Sanfrutos, Remigiusz Serwa et al. · Nature Chemistry · 2019 · 126 citations

Protein Chemistry, Protein Assembly, Biochemistry +8

Discovery of a Potent and Selective Covalent Inhibitor and Activity-Based Probe for the Deubiquitylating Enzyme UCHL1, with Antifibrotic Activity

Nattawadee Panyain, Aurélien Godinat, Thomas Lanyon‐Hogg et al. · Journal of the American Chemical Society · 2020 · 107 citations · Full text

Drug Target, Selective Uchl1 Probe, Chemical Biology +25

Topological Analysis of Hedgehog Acyltransferase, a Multipalmitoylated Transmembrane Protein

Antonio D. Konitsiotis, Biljana Jovanović, Paulina Ciepla et al. · Journal of Biological Chemistry · 2014 · 60 citations · Full text

Protein Function, Signal Transduction, Signaling Pathway +13

Structure, mechanism, and inhibition of Hedgehog acyltransferase

Claire E. Coupland, Sebastian A. Andrei, T. Bertie Ansell et al. · Molecular Cell · 2021 · 54 citations · Full text

Characterization of Hedgehog Acyltransferase Inhibitors Identifies a Small Molecule Probe for Hedgehog Signaling by Cancer Cells

Ursula R. Rodgers, Thomas Lanyon‐Hogg, Naoko Masumoto et al. · ACS Chemical Biology · 2016 · 46 citations · Full text

Cell Death, Cancer Biology, Sonic Hedgehog +19