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Melissa A. Farrow, Nicole M. Chumbler, Lynne A. Lapierre, +4

Proceedings of the National Academy of Sciences

ToxinologyMicrobial PathogensLipid PeroxidationImmunologyCell Death +21

Conditional expression of Mycobacterium smegmatis ftsZ, an essential cell division gene

Jarosław Dziadek, Stacey A. Rutherford, Murty V. Madiraju, +2

Microbiology

Crystal structure of Clostridium difficile toxin A

Nicole M. Chumbler, Stacey A. Rutherford, Zhifen Zhang, +7

Nature Microbiology

Microbial ToxinCrystal StructureToxinologyProtein X-ray CrystallographyMolecular Biology +4

Structural Determinants of Clostridium difficile Toxin A Glucosyltransferase Activity

Rory N. Pruitt, Nicole M. Chumbler, Stacey A. Rutherford, +4

Journal of Biological Chemistry

Microbial ToxinProtein FunctionRap Family GtpasesToxinologyBiochemistry +12

Intestinal bile acids directly modulate the structure and function of <i>C. difficile</i> TcdB toxin

John Tam, Simoun Icho, Evelyn Utama, +7

Proceedings of the National Academy of Sciences

Physiological consequences associated with overproduction of Mycobacterium tuberculosis FtsZ in mycobacterial hosts

Jarosław Dziadek, Murty V. Madiraju, Stacey A. Rutherford, +2

Microbiology

Inactivation of Src Family Tyrosine Kinases by Reactive Oxygen Species in Vivo

Hua Tang, Qin Hao, Stacey A. Rutherford, +2

Journal of Biological Chemistry

Lipid PeroxidationReactive Oxygen SpeciesRedox BiologyCellular PhysiologyOxidative Stress +16

Thrombin induces endocytosis of endoglin and type-II TGF-β receptor and down-regulation of TGF-β signaling in endothelial cells

Hua Tang, Brad Low, Stacey A. Rutherford, +1

Blood

Integrated, High-Throughput, Multiomics Platform Enables Data-Driven Construction of Cellular Responses and Reveals Global Drug Mechanisms of Action

Jeremy L. Norris, Melissa A. Farrow, Danielle Gutierrez, +28

Journal of Proteome Research

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Epitopes and Mechanism of Action of the Clostridium difficile Toxin A-Neutralizing Antibody Actoxumab

Lorraine D. Hernandez, Heather K. Kroh, Edward J. Hsieh, +16

Journal of Molecular Biology

Microbial ToxinToxinologyImmunologyAntibody ScreeningAntibody Engineering +4