Jonathan J. Chen

JAK–STAT Pathway Activation in Malignant and Nonmalignant Cells Contributes to MPN Pathogenesis and Therapeutic Response

Maria Kleppe, Minsuk Kwak, Priya Koppikar et al. · Cancer Discovery · 2015 · 315 citations · Full text

Medicine, Hematology, Pharmacology +17

Synergistic IL-6 and IL-8 paracrine signalling pathway infers a strategy to inhibit tumour cell migration

Hasini Jayatilaka, Pranay Tyle, Jonathan J. Chen et al. · Nature Communications · 2017 · 186 citations · Full text

Medicine, Cancer Biology, Oncology +16

High-Throughput Secretomic Analysis of Single Cells to Assess Functional Cellular Heterogeneity

Yao Lu, Jonathan J. Chen, Luye Mu et al. · Analytical Chemistry · 2013 · 181 citations

Life Sciences, Cell Biology, Molecular Biology +15

A microchip platform for interrogating tumor–macrophage paracrine signaling at the single-cell level

Meltem Elitaş, Kara Brower, Yao Lu et al. · Lab on a Chip · 2014 · 57 citations

Life Sciences, Immunology, Oncology +17

Developing an in silico pipeline for faster drug candidate discovery: Virtual high throughput screening with the Signature molecular descriptor using support vector machine models

Jonathan J. Chen, Donald P. Visco · Chemical Engineering Science · 2016 · 39 citations

Pharmacy, Medicinal Chemistry, Computational Medicinal Chemistry +16