Leonardo M. Loscalzo

Central nervous system depressant action of flavonoid glycosides

Sebastián P. Fernández, Cristina Wasowski, Leonardo M. Loscalzo et al. · European Journal of Pharmacology · 2006 · 280 citations

Flavonoid Glycosides, Medicine, Glycobiology +5

Opioid receptors are involved in the sedative and antinociceptive effects of hesperidin as well as in its potentiation with benzodiazepines

Leonardo M. Loscalzo, Cristina Wasowski, Alejandro C. Paladini et al. · European Journal of Pharmacology · 2007 · 71 citations

Health Sciences, Opioid Receptors, Pain Medicine +12

In vitro binding affinities of a series of flavonoids for μ-opioid receptors. Antinociceptive effect of the synthetic flavonoid 3,3-dibromoflavanone in mice

Josefina Higgs, Cristina Wasowski, Leonardo M. Loscalzo et al. · Neuropharmacology · 2013 · 46 citations · Full text

Molecular Pharmacology, Synthetic Flavonoid 3,3-Dibromoflavanone, Pharmacological Study +13

Hesperidin, a flavonoid glycoside with sedative effect, decreases brain pERK1/2 levels in mice

María Cecilia Martínez, Sebastián P. Fernández, Leonardo M. Loscalzo et al. · Pharmacology Biochemistry and Behavior · 2009 · 37 citations

Brain Perk1/2 Levels, Molecular Pharmacology, Flavonoid Glycoside +13

Hesperidin induces antinociceptive effect in mice and its aglicone, hesperetin, binds to μ-opioid receptor and inhibits GIRK1/2 currents

Leonardo M. Loscalzo, Tin T. Yow, Cristina Wasowski et al. · Pharmacology Biochemistry and Behavior · 2011 · 32 citations · Full text