Emmanuel Ségéral

SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by Vpx

Nadine Laguette, Bijan Sobhian, Nicoletta Casartelli et al. · Nature · 2011 · 1.5K citations

Life Sciences, Immunology, Infectious Diseases +12

ATF4 Degradation Relies on a Phosphorylation-Dependent Interaction with the SCF^βTrCPUbiquitin Ligase

Irina Lassot, Emmanuel Ségéral, Clarisse Berlioz‐Torrent et al. · Molecular and Cellular Biology · 2001 · 257 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

Two Dimerization Domains in the Trans-activation Response RNA-binding Protein (TRBP) Individually Reverse the Protein Kinase R Inhibition of HIV-1 Long Terminal Repeat Expression

Aı̈cha Daher, M. Longuet, Dominique Dorin et al. · Journal of Biological Chemistry · 2001 · 102 citations · Full text

Life Sciences, Biology, Molecular Biology +16

von Hippel–Lindau binding protein 1-mediated degradation of integrase affects HIV-1 gene expression at a postintegration step

Aurélie Mousnier, Nicole J. Kubat, Aurélie Massias-Simon et al. · Proceedings of the National Academy of Sciences · 2007 · 88 citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +17

HIV-1 Vpu Sequesters β-Transducin Repeat-containing Protein (βTrCP) in the Cytoplasm and Provokes the Accumulation of β-Catenin and Other SCFβTrCP Substrates

Corinne Besnard‐Guérin, Nadia Belaïdouni, Irina Lassot et al. · Journal of Biological Chemistry · 2003 · 85 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14