Rafaela Gladysz

Discovery and SAR of Novel and Selective Inhibitors of Urokinase Plasminogen Activator (uPA) with an Imidazo[1,2-<i>a</i>]pyridine Scaffold

Rafaela Gladysz, Yves Adriaenssens, Hans De Winter et al. · Journal of Medicinal Chemistry · 2015 · 37 citations · Full text

Selective Inhibitors, Pharmacotherapy, Chemical Biology +20

Spectrophores as one-dimensional descriptors calculated from three-dimensional atomic properties: applications ranging from scaffold hopping to multi-target virtual screening

Rafaela Gladysz, Fábio Mendes dos Santos, Wilfried Langenaeker et al. · Journal of Cheminformatics · 2018 · 24 citations · Full text

Inhibitor screening and enzymatic activity determination for autophagy target Atg4B using a gel electrophoresis-based assay

Matthias Cleenewerck, Mandy O. J. Grootaert, Rafaela Gladysz et al. · European Journal of Medicinal Chemistry · 2016 · 15 citations · Full text

Cell Autophagy, Mitophagy, Autoimmune Disease +15

Efforts towards an On‐Target Version of the Groebke–Blackburn–Bienaymé (GBB) Reaction for Discovery of Druglike Urokinase (uPA) Inhibitors

Rafaela Gladysz, Johannes Vrijdag, Dries Van Rompaey et al. · Chemistry - A European Journal · 2019 · 14 citations

Combinatorial Chemistry, On‐target Version, Medicinal Chemistry +15

The first potent diphenyl phosphonate KLK4 inhibitors with unexpected binding kinetics

Jeroen Van Soom, Giuliana Cuzzucoli Crucitti, Rafaela Gladysz et al. · MedChemComm · 2015 · 11 citations

Molecular Pharmacology, Medicinal Chemistry, Drug Target +13