A highly potent and long-acting oral inhibitor of human renin.

Kunio Hiwada, Takeshi Kokubu, E Murakami, +5

Hypertension

PharmacotherapyExperimental PharmacologyBlood PressureDrug ResistanceMolecular Pharmacology +14

Polysplenia Syndrome with Various Visceral Anomalies in an Adult: Embryological and Clinical Considerations.

Shinjiro Muneta, Shuji Sakai, Hiroshi Fukuda, +2

Internal Medicine

Blood pressure and heart rate variability in elderly patients with isolated systolic hypertension.

Shinjiro Muneta, E Murakami, Tatsuo Sumimoto, +4

PubMed

In Vitro Inhibition of Human Renin by Statine-Containing Tripeptide Renin Inhibitor (ES-1005)

Takeshi Kokubu, Kunio Hiwada, E Murakami, +5

Journal of Cardiovascular Pharmacology

Molecular PharmacologyMedicinal ChemistryUrologyVitro InhibitionBiochemistry +13

Personality Characteristics of Patients with "White Coat" Hypertension.

Shinjiro Muneta, Takamasa Kobayashi, Isao Matsumoto

Hypertension Research

ES-8891, an orally active inhibitor of human renin.

Tomokuni Kokubu, K Hiwada, E Murakami, +3

Hypertension

Molecular PharmacologyMedicinal ChemistryPharmacological StudyBiochemistrySodium Homeostasis +13

The effect of the renin inhibitor ES-1005 on the expression of the kidney renin gene in sodium-depleted marmosets

Yutaka Kitami, K Hiwada, Eiki Murakam, +2

Journal of Hypertension

Influence of age and severity of hypertension on blood pressure response to isometric handgrip exercise.

Takumi Sumimoto, Motoharu Hamada, Shinjiro Muneta, +5

PubMed

Kidney renin gene expression after renin inhibition in the marmoset

Yutaka Kitami, Kunio Hiwada, Eiki Murakami, +3

Clinical Science

HypertensionRenal InflammationPharmacotherapyRenin SynthesisMolecular Pharmacology +22

Effect of L-threo-3,4-dihydroxyphenylserine on orthostatic hypotension in a patient with spinal cord injury.

Shinjiro Muneta, TAKERU IWATA, Kunio Hiwada, +3

Japanese Circulation Journal

HypertensionUrologySpinal Cord InjuryClinical InjuryMedicine +13