Cécile Delorme

Discovery and Optimization of Pyrimidone Indoline Amide PI3Kβ Inhibitors for the Treatment of Phosphatase and Tensin Homologue (PTEN)-Deficient Cancers

Victor Certal, Jean‐Christophe Carry, Frank Halley et al. · Journal of Medicinal Chemistry · 2014 · 85 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Discovery and Optimization of New Benzimidazole- and Benzoxazole-Pyrimidone Selective PI3Kβ Inhibitors for the Treatment of Phosphatase and TENsin homologue (PTEN)-Deficient Cancers

Victor Certal, Frank Halley, Angéla Virone-Oddos et al. · Journal of Medicinal Chemistry · 2012 · 53 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Tricyclic Series of Heat Shock Protein 90 (Hsp90) Inhibitors Part I: Discovery of Tricyclic Imidazo[4,5-<i>c</i>]pyridines as Potent Inhibitors of the Hsp90 Molecular Chaperone

François Vallée, Chantal Carrez, Fabienne Pilorge et al. · Journal of Medicinal Chemistry · 2011 · 47 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

SAR156497, an Exquisitely Selective Inhibitor of Aurora Kinases

Jean‐Christophe Carry, François Clerc, Hervé Minoux et al. · Journal of Medicinal Chemistry · 2014 · 39 citations · Full text

Medicine, Medicinal Chemistry, Oncology +14

Concomitant Inhibition of PI3Kβ and BRAF or MEK in PTEN-Deficient/ <i>BRAF</i> -Mutant Melanoma Treatment: Preclinical Assessment of SAR260301 Oral PI3K <b>β</b> -Selective Inhibitor

Hélène Bonnevaux, Olivier Lemaitre, Loi͏̈c Vincent et al. · Molecular Cancer Therapeutics · 2016 · 30 citations

Medicine, Oncology, Pharmacology +14