Phosphorylation of p47<i>^p</i><i>^hox</i>Sites by PKC α, βΙΙ, δ, and ζ:  Effect on Binding to p22<i>^p</i><i>^hox</i>and on NADPH Oxidase Activation

Alexandre Fontayne, Pham My‐Chan Dang, Marie‐Anne Gougerot‐Pocidalo, +1

Biochemistry

Pkc αBioorganic ChemistryAldo-keto ReductaseLipid PeroxidationMolecular Biology +19

Protein Kinase C ζ Phosphorylates a Subset of Selective Sites of the NADPH Oxidase Component p47 <i>phox</i> and Participates in Formyl Peptide-Mediated Neutrophil Respiratory Burst

Pham My‐Chan Dang, Alexandre Fontayne, Jacques Hakim, +2

The Journal of Immunology

Molecular cloning, characterization, genomic organization and promoter analysis of the α1,6-fucosyltransferase gene (fut8) expressed in the rat hybridoma cell line YB2/0

Béatrice Teylaert, Edwige Meurice, Marie Bobowski, +5

BMC Biotechnology

Fc Sialylation Prolongs Serum Half-Life of Therapeutic Antibodies

Mathilde Bas, Aurélie Terrier, Émilie Jacque, +14

The Journal of Immunology

The humanized anti-glycoprotein Ib monoclonal antibody h6B4-Fab is a potent and safe antithrombotic in a high shear arterial thrombosis model in baboons

Alexandre Fontayne, Muriel Meiring, Seb Lamprecht, +4

Thrombosis and Haemostasis

Development of a drug delivery system for efficient alveolar delivery of a neutralizing monoclonal antibody to treat pulmonary intoxication to ricin

Renaud Respaud, D. Marchand, Thibaut Pelat, +15

Journal of Controlled Release

Cell-based Drug DeliveryPolymer-drug ConjugateImmunologyPharmacologyPulmonary Pharmacology +6

Selection of IgG Variants with Increased FcRn Binding Using Random and Directed Mutagenesis: Impact on Effector Functions

Céline Monnet, Sylvie Jorieux, Nathalie Fournier, +5

Frontiers in Immunology

EngineeringVivo Half-lifeGeneticsImmunologyMolecular Biology +25

Combined glyco- and protein-Fc engineering simultaneously enhance cytotoxicity and half-life of a therapeutic antibody

Céline Monnet, Sylvie Jorieux, Nathalie Souyris, +10

mAbs

Low expression of the β-ENaC subunit impairs lung fluid clearance in the mouse

Nadia Randrianarison, Christine Clérici, Chrystophe Ferreira, +6

American Journal of Physiology-Lung Cellular and Molecular Physiology

Lung InflammationCellular PhysiologyBaseline Afcβ-Enac Subunit ImpairsMembrane Transport +18

Rational humanization of the powerful antithrombotic anti-GPIbalpha antibody: 6B4.

Alexandre Fontayne, Karen Vanhoorelbeke, Inge Pareyn, +6

PubMed

Immunocytochemical TechniqueImmunologyImmune SystemImmunotherapyMonoclonal Antibody 6B4 +15