ACVR1/JAK1/JAK2 inhibitor momelotinib reverses transfusion dependency and suppresses hepcidin in myelofibrosis phase 2 trial

Stephen T. Oh, Moshe Talpaz, Aaron T. Gerds, +15

Blood Advances

T Cell–Derived IL-17 Mediates Epithelial Changes in the Airway and Drives Pulmonary Neutrophilia

Laura K. Fogli, Mark S. Sundrud, Swati Goel, +14

The Journal of Immunology

AsthmaInflammatory Lung DiseaseLung InflammationImmunologyIl-17 Activity +16

Role of Dysregulated Cytokine Signaling and Bacterial Triggers in the Pathogenesis of Cutaneous T-Cell Lymphoma

Melania H. Fanok, Amy Sun, Laura K. Fogli, +16

Journal of Investigative Dermatology

InflammationCutaneous T-cell LymphomaDysregulated Cytokine SignalingAutoimmune DiseaseBacterial Triggers +9

North American ATLL has a distinct mutational and transcriptional profile and responds to epigenetic therapies

Urvi A. Shah, Elaine Y. Chung, Orsi Giricz, +30

Blood

SARS-CoV-2 Switches ‘on’ MAPK and NFκB Signaling via the Reduction of Nuclear DUSP1 and DUSP5 Expression

Swati Goel, Fatemeh Saheb Sharif‐Askari, Narjes Saheb Sharif‐Askari, +8

Frontiers in Pharmacology

On-admission anemia predicts mortality in COVID-19 patients: A single center, retrospective cohort study

Seung Mi Oh, John P. Skendelas, Eric J. Macdonald, +7

The American Journal of Emergency Medicine

Single CenterOn-admission AnemiaLong CovidAplastic AnemiaCovid-19 Pandemic +7

Direct oral anticoagulants for myeloproliferative neoplasms: results from an international study on 442 patients

Tiziano Barbui, Valerio De Stefano, Alessandra Carobbio, +28

Leukemia

Hematological MalignancyThrombosisOncologyDirect Oral AnticoagulantsHematology +8

Safety and clinical activity of MEDI0562, a humanized OX40 agonist monoclonal antibody, in adult patients with advanced solid tumors

Bonnie S. Glisson, Rom S. Leidner, Robert L. Ferris, +12

Annals of Oncology

First-in-human phase I trial of a novel epothilone, KOS-1584

Miguel A. Villalona‐Calero, Swati Goel, Larry J. Schaaf, +7

Journal of Clinical Oncology

Molecular PharmacologyTumor BiologyOncologyPreclinical Drug EvaluationMedicine +13

SARS-CoV-2 attenuates corticosteroid sensitivity by suppressing DUSP1 expression and activating p38 MAPK pathway

Fatemeh Saheb Sharif‐Askari, Narjes Saheb Sharif‐Askari, Swati Goel, +5

European Journal of Pharmacology

Sars-cov-2 AttenuatesCytokineSignal TransductionImmunologyPathology +7