Takehito Isobe

The Fibroblast Growth Factor Receptor Genetic Status as a Potential Predictor of the Sensitivity to CH5183284/Debio 1347, a Novel Selective FGFR Inhibitor

Yoshito Nakanishi, Nukinori Akiyama, Toshiyuki Tsukaguchi et al. · Molecular Cancer Therapeutics · 2014 · 119 citations · Full text

Radiation Oncology, Fgf Receptors, Novel Therapy +13

Discovery of [5-Amino-1-(2-methyl-3<i>H</i>-benzimidazol-5-yl)pyrazol-4-yl]-(1<i>H</i>-indol-2-yl)methanone (CH5183284/Debio 1347), An Orally Available and Selective Fibroblast Growth Factor Receptor (FGFR) Inhibitor

Hirosato Ebiike, Naoki Taka, Masayuki Matsushita et al. · Journal of Medicinal Chemistry · 2016 · 37 citations · Full text

Drug Target, Chemoprevention Strategy, Human Growth +25

[S 100 protein].

Takehito Isobe, Toru Okuyama · PubMed · 1984 · 25 citations

Protein Chemistry, Protein Quality Control, Protein Function +8

Conduction and contraction properties of human iPS cell-derived cardiomyocytes: analysis by motion field imaging compared with the guinea-pig isolated heart model

Takehito Isobe, Masaki Honda, Ryuichi Komatsu et al. · The Journal of Toxicological Sciences · 2018 · 14 citations · Full text

Sensitivity of common marmosets to detect drug-induced QT interval prolongation: Moxifloxacin case study

Ryuichi Komatsu, Masaki Honda, Henry H. Holzgrefe et al. · Journal of Pharmacological and Toxicological Methods · 2010 · 12 citations

Therapeutic Drug Monitoring, Pharmacology, Common Marmosets +6