Barbara Martins Da Costa

Metabolic engineering against the arginine microenvironment enhances CAR-T cell proliferation and therapeutic activity

Livingstone Fultang, Sarah Booth, Orli Yogev et al. · Blood · 2020 · 178 citations · Full text

Life Sciences, Biochemistry, Biotechnology +14

Sulfopin is a covalent inhibitor of Pin1 that blocks Myc-driven tumors in vivo

Christian Dubiella, Benika J. Pinch, Kazuhiro Koikawa et al. · Nature Chemical Biology · 2021 · 148 citations · Full text

Medicine, Molecular Biology, Oncology +14

Indisulam targets RNA splicing and metabolism to serve as a therapeutic strategy for high-risk neuroblastoma

Anke Nijhuis, Arti Sikka, Orli Yogev et al. · Nature Communications · 2022 · 117 citations · Full text

Medicine, Biochemistry, Oncology +17

<i>In Vivo</i> Modeling of Chemoresistant Neuroblastoma Provides New Insights into Chemorefractory Disease and Metastasis

Orli Yogev, Gilberto S. Almeida, Karen Barker et al. · Cancer Research · 2019 · 80 citations · Full text

Medicine, Cancer Biology, Oncology +15

Therapeutic vulnerabilities in the DNA damage response for the treatment of ATRX mutant neuroblastoma

Sally L. George, Federica Lorenzi, David S. King et al. · EBioMedicine · 2020 · 79 citations · Full text

Medicine, Genetics, Oncology +15