CXCR4 Is Required for Leukemia-Initiating Cell Activity in T Cell Acute Lymphoblastic Leukemia

Diana Passaro, Marta Irigoyen, Claire Catherinet, +5

Cancer Cell

Leukemia-initiating Cell ActivityImmunologyCellular Immune ResponseAdult T-cell Leukemia-lymphomaMedicine +2

Biallelic inactivation of REV7 is associated with Fanconi anemia

Dominique Bluteau, Julien Masliah-Planchon, Connor S. Clairmont, +13

Journal of Clinical Investigation

Fa PhenotypeGeneticsPathologyBiallelic InactivationTranscriptional Regulation +15

Clonal hematopoiesis driven by chromosome 1q/MDM4 trisomy defines a canonical route toward leukemia in Fanconi anemia

Marie Sébert, Stéphanie Gachet, Thierry Leblanc, +62

Cell stem cell

Hematological MalignancyChromatinFanconi AnemiaGeneticsHematology +5

Large-scale circular RNA deregulation in T-ALL: unlocking unique ectopic expression of molecular subtypes

Alessia Buratin, Maddalena Paganin, Enrico Gaffo, +13

Blood Advances

EngineeringGeneticsImmunologyMolecular BiologyPathology +17

Leukemia-initiating cell activity requires calcineurin in T-cell acute lymphoblastic leukemia

Stéphanie Gachet, Eulàlia Genescà, Diana Passaro, +11

Leukemia

Hematological MalignancySignal TransductionLeukemia-initiating Cell ActivityCell SignalingImmunology +5

Deletion 6q Drives T-cell Leukemia Progression by Ribosome Modulation

Stéphanie Gachet, Tiama El-Chaar, David Avran, +24

Cancer Discovery

Concurrent <i>CDX2 cis</i>-deregulation and <i>UBTF::ATXN7L3</i> fusion define a novel high-risk subtype of B-cell ALL

Marie Passet, Rathana Kim, Stéphanie Gachet, +25

Blood

Mixed-phenotype Acute LeukemiaGeneticsImmunologyCrispr Interference ExperimentsEpigenetics +17

Adult Low-Hypodiploid Acute Lymphoblastic Leukemia Emerges from Preleukemic <i>TP53</i> -Mutant Clonal Hematopoiesis

Rathana Kim, Hugo Bergugnat, Lise Larcher, +25

Blood Cancer Discovery

RelB-Dependent Stromal Cells Promote T-Cell Leukemogenesis

Nuno R. dos Santos, Maryvonne Williame, Stéphanie Gachet, +5

PLoS ONE

A Tumor Suppressor Enhancer of <i>PTEN</i> in T-cell Development and Leukemia

Luca Tottone, Olga Lancho, Jui-Wan Loh, +20

Blood Cancer Discovery