Discriminating α-synuclein strains in Parkinson’s disease and multiple system atrophy

Mohammad Shahnawaz, Abhisek Mukherjee, Sandra Pritzkow, +12

Nature

Neurodegenerative DiseasesDegenerative DiseasesParkinson DiseaseMultiple System AtrophyDegenerative Disease +6

Cellulose from the green macroalgae Ulva lactuca: isolation, characterization, optotracing, and production of cellulose nanofibrils

Niklas Wahlström, Ulrica Edlund, Henrik Pavia, +7

Cellulose

Structure-based drug design identifies polythiophenes as antiprion compounds

U. Herrmann, Anne K. Schütz, Hamid Shirani, +17

Science Translational Medicine

The Structural Basis for Optimal Performance of Oligothiophene‐Based Fluorescent Amyloid Ligands: Conformational Flexibility is Essential for Spectral Assignment of a Diversity of Protein Aggregates

Therése Klingstedt, Hamid Shirani, K. O. Andreas Åslund, +4

Chemistry - A European Journal

A Palette of Fluorescent Thiophene‐Based Ligands for the Identification of Protein Aggregates

Hamid Shirani, Mathieu Linares, Christina J. Sigurdson, +3

Chemistry - A European Journal

Supramolecular AssemblyEngineeringOrganic ChemistryAnalytical UltracentrifugationChemistry +16

Real-time imaging of mitochondrial redox reveals increased mitochondrial oxidative stress associated with amyloid β aggregates in vivo in a mouse model of Alzheimer’s disease

María Calvo-Rodríguez, Elizabeth K. Kharitonova, Austin Snyder, +8

Molecular Neurodegeneration

In vivo detection of tau fibrils and amyloid β aggregates with luminescent conjugated oligothiophenes and multiphoton microscopy

María Calvo-Rodríguez, Steven S. Hou, Austin Snyder, +4

Acta Neuropathologica Communications

Antifouling activity of synthesized peptide analogs of the sponge metabolite barettin

Martin Sjögren, A. E. Johnson, Erik Hedner, +6

Peptides

Sponge Metabolite BarettinBiochemistryMedicineNatural SciencesPeptide Engineering +7

Distinct Spacing Between Anionic Groups: An Essential Chemical Determinant for Achieving Thiophene‐Based Ligands to Distinguish β‐Amyloid or Tau Polymorphic Aggregates

Therése Klingstedt, Hamid Shirani, Jasmin Mahler, +5

Chemistry - A European Journal

EngineeringMolecular BiologyNeurochemical BiomarkersPeptide ScienceChemistry +20

Pentameric Thiophene‐Based Ligands that Spectrally Discriminate Amyloid‐β and Tau Aggregates Display Distinct Solvatochromism and Viscosity‐Induced Spectral Shifts

Rozalyn Simon, Hamid Shirani, K. O. Andreas Åslund, +4

Chemistry - A European Journal

Spectrally Discriminate Amyloid‐βEngineeringSupramolecular AssemblyMolecule-based MaterialNeurochemical Biomarkers +18