Jean‐François Guichou

TLR-independent control of innate immunity in Caenorhabditis elegans by the TIR domain adaptor protein TIR-1, an ortholog of human SARM

Carole Couillault, Nathalie Pujol, Jérôme Reboul et al. · Nature Immunology · 2004 · 485 citations

Signal Transduction, Adaptive Immune System, Medicine +9

e-Drug3D: 3D structure collections dedicated to drug repurposing and fragment-based drug design

Émilie Pihan, Lionel Colliandre, Jean‐François Guichou et al. · Bioinformatics · 2012 · 134 citations · Full text

Characterization of the Interaction between Retinoic Acid Receptor/Retinoid X Receptor (RAR/RXR) Heterodimers and Transcriptional Coactivators through Structural and Fluorescence Anisotropy Studies

Vivian Pogenberg, Jean‐François Guichou, Valérie Vivat‐Hannah et al. · Journal of Biological Chemistry · 2004 · 130 citations · Full text

Fragment-based discovery of a new family of non-peptidic small-molecule cyclophilin inhibitors with potent antiviral activities

Abdelhakim Ahmed‐Belkacem, Lionel Colliandre, Nazim Ahnou et al. · Nature Communications · 2016 · 89 citations · Full text

Small-Molecule Inhibitors of Cyclophilins Block Opening of the Mitochondrial Permeability Transition Pore and Protect Mice From Hepatic Ischemia/Reperfusion Injury

Mathieu Panel, Isaac Ruiz, Rozenn Brillet et al. · Gastroenterology · 2019 · 78 citations · Full text

Inflammation, Mitochondrial Function, Biochemistry +13