Leonardo Giovannoni

Immunoscintigraphic detection of the ED-B domain of fibronectin, a marker of angiogenesis, in patients with cancer.

Monica Santimaria, G Moscatelli, Giuseppe Viale et al. · PubMed · 2003 · 294 citations

Medicine, Immunology, Oncology +15

Increased binding affinity and valence of recombinant antibody fragments lead to improved targeting of tumoral angiogenesis.

Francesca Viti, Lorenzo Tarli, Leonardo Giovannoni et al. · PubMed · 1999 · 208 citations

Medicine, Cancer Biology, Oncology +17

The tumour-targeting human L19-IL2 immunocytokine: Preclinical safety studies, phase I clinical trial in patients with solid tumours and expansion into patients with advanced renal cell carcinoma

Manfred Johannsen, Gianluca Spitaleri, Giuseppe Curigliano et al. · European Journal of Cancer · 2010 · 185 citations

Medicine, Immunology, Oncology +12

Intralesional administration of L19-IL2/L19-TNF in stage III or stage IVM1a melanoma patients: results of a phase II study

Riccardo Danielli, Roberto Patuzzo, Anna Maria Di Giacomo et al. · Cancer Immunology Immunotherapy · 2015 · 179 citations · Full text

Medicine, Immunology, Oncology +15

Expression of the oncofetal ED-B–containing fibronectin isoform in hematologic tumors enables ED-B–targeted 131I-L19SIP radioimmunotherapy in Hodgkin lymphoma patients

Stefanie Sauer, Paola Anna Erba, Mario Petrini et al. · Blood · 2009 · 171 citations

Medicine, Hematology, Oncology +14