Statin Therapy Reduces the Mycobacterium tuberculosis Burden in Human Macrophages and in Mice by Enhancing Autophagy and Phagosome Maturation

Suraj P. Parihar, Reto Guler, Rethabile Khutlang, +6

The Journal of Infectious Diseases

Batf2/Irf1 Induces Inflammatory Responses in Classically Activated Macrophages, Lipopolysaccharides, and Mycobacterial Infection

Sugata Roy, Reto Guler, Suraj P. Parihar, +13

The Journal of Immunology

Lung InflammationClassically Activated MacrophagesAdaptive Immune SystemInnate Immune SystemImmunology +25

Allergic airway disease is unaffected by the absence of IL-4Rα–dependent alternatively activated macrophages

Natalie E. Nieuwenhuizen, Frank Kirstein, Jaisubash Jayakumar, +5

Journal of Allergy and Clinical Immunology

Macrophage BiologyInflammationCytokineInflammatory Lung DiseaseAllergy +8

Deletion of IL-4 Receptor Alpha on Dendritic Cells Renders BALB/c Mice Hypersusceptible to Leishmania major Infection

Ramona Hurdayal, Natalie E. Nieuwenhuizen, Mélanie Revaz‐Breton, +4

Columbia Academic Commons (Columbia University)

Adaptive Immune SystemInnate Immune SystemImmune RegulationImmunologyIl-4 Receptor Alpha +22

Topical Simvastatin as Host-Directed Therapy against Severity of Cutaneous Leishmaniasis in Mice

Suraj P. Parihar, Mary‐Anne Hartley, Ramona Hurdayal, +2

Scientific Reports

InflammationSimvastatin TreatmentTopical SimvastatinImmunotoxicologyMedicine +12

Protein kinase C-delta (PKCδ), a marker of inflammation and tuberculosis disease progression in humans, is important for optimal macrophage killing effector functions and survival in mice

Suraj P. Parihar, Mumin Ozturk, Mohlopheni J. Marakalala, +12

Mucosal Immunology

IL-4–producing B cells regulate T helper cell dichotomy in type 1- and type 2-controlled diseases

Ramona Hurdayal, Hlumani Ndlovu, Mélanie Revaz‐Breton, +4

Proceedings of the National Academy of Sciences

Anti-peptide antibodies differentiate between plasmodial lactate dehydrogenases

Ramona Hurdayal, Ikechukwu Achilonu, David Choveaux, +2

Peptides

Cellular EnzymologyBiochemistryNatural SciencesBioanalysisAntibody Screening +3

Plasmodium glyceraldehyde-3-phosphate dehydrogenase: A potential malaria diagnostic target

Robert Krause, Ramona Hurdayal, David Choveaux, +3

Experimental Parasitology

BiochemistryNatural SciencesBioanalysisMalariaMolecular Biology +5

Unravelling the unsolved paradoxes of cytokine families in host resistance and susceptibility to Leishmania infection

Bernard Osero, Raphael Taiwo Aruleba, Frank Brombacher, +1

Cytokine X