Biophysical Properties of Human Antibody Variable Domains

Stefan Ewert, Thomas Huber, Annemarie Honegger, +1

Journal of Molecular Biology

ImmunologyAntibody EngineeringBiophysical PropertiesMolecular BiophysicsAntibody Screening +2

G Protein-Coupled Receptors Self-Assemble in Dynamics Simulations of Model Bilayers

Xavier Périole, Thomas Huber, ‪Siewert J. Marrink, +1

Journal of the American Chemical Society

Recurrent activating mutations of G-protein-coupled receptor CYSLTR2 in uveal melanoma

Amanda R. Moore, Emilie Ceraudo, Jessica Sher, +11

Nature Genetics

Signal TransductionG Protein-coupled ReceptorReceptor Tyrosine KinasePhotocarcinogenesisMelanoma +5

Curvature and Hydrophobic Forces Drive Oligomerization and Modulate Activity of Rhodopsin in Membranes

Ana Vitória Botelho, Thomas Huber, Thomas P. Sakmar, +1

Biophysical Journal

Membrane StructureProteinlipid InteractionMembrane BiophysicsBiochemistryProtein Folding +8

Structural Determinants of the Supramolecular Organization of G Protein-Coupled Receptors in Bilayers

Xavier Périole, Adam M. Knepp, Thomas P. Sakmar, +2

Journal of the American Chemical Society

Proteinlipid InteractionProtein AssemblySupramolecular OrganizationMolecular DynamicsDimer Orientation +20

Bilateral olfactory sensory input enhances chemotaxis behavior

Matthieu Louis, Thomas Huber, Richard Benton, +2

Nature Neuroscience

Neurobiological MechanismHealth SciencesNeurophysiologyBehavioral NeurosciencePhysiology +7

FTIR analysis of GPCR activation using azido probes

Shixin Ye, Thomas Huber, Reiner Vogel, +1

Nature Chemical Biology

Ftir AnalysisAnalytical InstrumentationNatural SciencesSpectroscopyInfrared Spectroscopy +6

Opsin Is a Phospholipid Flippase

I. A. Menon, Thomas Huber, Sumana Sanyal, +7

Current Biology

Proteinlipid InteractionSignal TransductionOxysterolBiochemistryNatural Sciences +2

Site-specific Incorporation of Keto Amino Acids into Functional G Protein-coupled Receptors Using Unnatural Amino Acid Mutagenesis

Shixin Ye, Caroline Köhrer, Thomas Huber, +5

Journal of Biological Chemistry

Molecular BiologyChemical BiologyMolecular PharmacologySite-specific IncorporationCell Signaling +18

Functional Role of the “Ionic Lock”—An Interhelical Hydrogen-Bond Network in Family A Heptahelical Receptors

Reiner Vogel, Mohana Mahalingam, Steffen Lüdeke, +3

Journal of Molecular Biology

Signal TransductionBiochemistryNatural SciencesChemical BondHydrogen Bond +4