Mark Wigglesworth - Concepedia

Author

Mark Wigglesworth

Also Known As

Dr. Mark Wigglesworth, M Wigglesworth, M. J. Wigglesworth, M. Wigglesworth, M.J. Wigglesworth, Mark J Wigglesworth, Mark J. Wigglesworth, Mark Wigglesworth, Wigglesworth, Mark 1964-

Publications

3.5K

Citations

H-Index

Concepts

All Affiliations

AstraZeneca (United Kingdom)GlaxoSmithKline (United Kingdom)AstraZeneca (Sweden)University of Cambridge University of Leeds

About

Mark Wigglesworth is an author at AstraZeneca (United Kingdom) specializing in medicine, pharmacology, and drug discovery.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	10	10	253
2	Natural Sciences	4	4	111
3	Engineering	2	2	37
4	Public Health	1	1	11
5	Allergy	1	1	67

Mark Wigglesworth

Publications

3.3K

Citations

H-Index

Page 1

	Year	Citations
The Orphan G Protein-coupled Receptors GPR41 and GPR43 Are Activated by Propionate and Other Short Chain Carboxylic Acids Andrew J. Brown, Susan M. Goldsworthy, Ashley Barnes, Journal of Biological Chemistry	2003	2.3K
Engineering a Model Cell for Rational Tuning of GPCR Signaling W. M. Shaw, Hitoshi Yamauchi, Jack Mead, Cell	2019	225
Screening β-Arrestin Recruitment for the Identification of Natural Ligands for Orphan G-Protein–Coupled Receptors C. Southern, Jennifer M. Cook, Zaynab Neetoo‐Isseljee, SLAS DISCOVERY	2013	177
Industrial scale high-throughput screening delivers multiple fast acting macrofilaricides Rachel H. Clare, Catherine Bardelle, Paul Harper, Nature Communications	2018	128
Identification of a novel asthma susceptibility gene on chromosome 1qter and its functional evaluation John H. White, Mathias Chiano, Mark Wigglesworth, Human Molecular Genetics AsthmaOpn3 Down-regulationFunctional EvaluationGeneticsGenetic Epidemiology	2008	67
Understanding Cytotoxicity and Cytostaticity in a High-Throughput Screening Collection Lewis Mervin, Qing Cao, Ian P. Barrett, ACS Chemical Biology Drug TargetToxicological MechanismEnrichment MetricsTop Ranking TargetsMedicinal Chemistry	2016	44
Non-peptidic antagonists of the CGRP receptor, BIBN4096BS and MK-0974, interact with the calcitonin receptor-like receptor via methionine-42 and RAMP1 via tryptophan-74 Philip S. Miller, James Barwell, David R. Poyner, Biochemical and Biophysical Research Communications	2009	41
A Perspective on Synthetic Biology in Drug Discovery and Development—Current Impact and Future Opportunities Florian David, A. M. Davis, Michael Gossing, SLAS DISCOVERY	2021	38
Discovery and Optimization of Allosteric Inhibitors of Mutant Isocitrate Dehydrogenase 1 (R132H IDH1) Displaying Activity in Human Acute Myeloid Leukemia Cells Stuart Jones, Jonathan Ahmet, Kelly Ayton, Journal of Medicinal Chemistry Myeloid DifferentiationAldo-keto ReductaseR132h Idh1Allosteric InhibitorsChemical Biology	2016	37
CGRP, adrenomedullin and adrenomedullin 2 display endogenous GPCR agonist bias in primary human cardiovascular cells Ashley Clark, N Mullooly, Dewi Safitri, Communications Biology	2021	32

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