Laura Jeacock

Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibition

Susan Wyllie, Stephen Brand, Michael G. Thomas et al. · Proceedings of the National Academy of Sciences · 2019 · 165 citations · Full text

Codon usage bias controls mRNA and protein abundance in trypanosomatids

Laura Jeacock, Joana Faria, David Horn · eLife · 2018 · 102 citations · Full text

Inducible high-efficiency CRISPR-Cas9-targeted gene editing and precision base editing in African trypanosomes

Eva Rico, Laura Jeacock, Julie Kovářová et al. · Scientific Reports · 2018 · 78 citations · Full text

Pentamidine Is Not a Permeant but a Nanomolar Inhibitor of the Trypanosoma brucei Aquaglyceroporin-2

Jie Song, Nicola Baker, Monja Rothert et al. · PLoS Pathogens · 2016 · 61 citations · Full text

Medicinal Chemistry, Drug Target, Tbaqp2 Glycerol Permeability +15

Aquaglyceroporin-null trypanosomes display glycerol transport defects and respiratory-inhibitor sensitivity

Laura Jeacock, Nicola Baker, Natalie Wiedemar et al. · PLoS Pathogens · 2017 · 43 citations · Full text

Proteinlipid Interaction, Glycerol Transport Defects, Biochemistry +14