Stephen Rettie

Accurate de novo design of hyperstable constrained peptides

Gaurav Bhardwaj, Vikram Khipple Mulligan, Christopher D. Bahl et al. · Nature · 2016 · 467 citations

Engineering, Computational Design, Drug Discovery +9

Comprehensive computational design of ordered peptide macrocycles

Parisa Hosseinzadeh, Gaurav Bhardwaj, Vikram Khipple Mulligan et al. · Science · 2017 · 220 citations · Full text

Pharmacy, Computational Design, Medicinal Chemistry +17

Accurate de novo design of membrane-traversing macrocycles

Gaurav Bhardwaj, Jacob O’Connor, Stephen Rettie et al. · Cell · 2022 · 170 citations · Full text

Pharmacy, Biochemistry, Medicinal Chemistry +17

Anchor extension: a structure-guided approach to design cyclic peptides targeting enzyme active sites

Parisa Hosseinzadeh, P. R. Watson, Timothy W. Craven et al. · Nature Communications · 2021 · 95 citations · Full text

Pharmacy, Biochemistry, Medicinal Chemistry +17

Cyclic peptide structure prediction and design using AlphaFold

Stephen Rettie, Katelyn V. Campbell, Asim K. Bera et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2023 · 80 citations · Full text

Life Sciences, Bioinformatics, Medicinal Chemistry +17