Efficient generation of recombinant adenovirus vectors by homologous recombination in Escherichia coli

Cécile Chartier, Eric Degryse, Murielle Gantzer, +3

Journal of Virology

Viral ReplicationEngineeringSynthetic VirologyMolecular BiologyEscherichia Coli +16

Immune Checkpoint Blockade, Immunogenic Chemotherapy or IFN-α Blockade Boost the Local and Abscopal Effects of Oncolytic Virotherapy

Laetitia Fend, Takahiro Yamazaki, Christelle Remy, +11

Cancer Research

Vectorization in an oncolytic vaccinia virus of an antibody, a Fab and a scFv against programmed cell death -1 (PD-1) allows their intratumoral delivery and an improved tumor-growth inhibition

Patricia Kleinpeter, Laetitia Fend, Christine Thioudellet, +16

OncoImmunology

Viral based vaccine TG4010 induces broadening of specific immune response and improves outcome in advanced NSCLC

Caroline Tosch, Bérangère Bastien, Luc Barraud, +7

Journal for ImmunoTherapy of Cancer

Sequential administration of MVA-based vaccines and PD-1/PD-L1-blocking antibodies confers measurable benefits on tumor growth and survival: Preclinical studies with MVA-βGal and MVA-MUC1 (TG4010) in a murine tumor model

Christelle Remy‐Ziller, Christine Thioudellet, Julie Hortelano, +8

Human Vaccines & Immunotherapeutics

By Binding CD80 and CD86, the Vaccinia Virus M2 Protein Blocks Their Interactions with both CD28 and CTLA4 and Potentiates CD80 Binding to PD-L1

Patricia Kleinpeter, Christelle Remy‐Ziller, Eline Winter, +18

Journal of Virology

ImmunologyViral PathogenesisImmunodominancePotentiates Cd80 BindingImmunotherapeutics +16

Intravenous Injection of MVA Virus Targets CD8+ Lymphocytes to Tumors to Control Tumor Growth upon Combinatorial Treatment with a TLR9 Agonist

Laetitia Fend, Tanja Gatard-Scheikl, Jacqueline Kintz, +6

Cancer Immunology Research

Mva-encoded AntigensImmunologyImmunoeditingEffector T-cell AccessImmunotherapeutics +19

Fusokine Interleukin-2/Interleukin-18, a Novel Potent Innate and Adaptive Immune Stimulator with Decreased Toxicity

Bruce Acres, Murielle Gantzer, Christelle Remy, +6

Cancer Research

ImmunotoxicologyInnate Immune SystemImmunologyImmune RegulationPathology +22

Safety, biodistribution and viral shedding of oncolytic vaccinia virus TG6002 administered intravenously in healthy beagle dogs

Jérémy Béguin, Murielle Gantzer, Isabelle Farine, +5

Scientific Reports

Oncolytic virotherapy with intratumoral injection of vaccinia virus TG6002 and 5-fluorocytosine administration in dogs with malignant tumors

Jérémy Béguin, Eve Laloy, Sandrine Cochin, +13

Molecular Therapy — Oncolytics