Next-generation active immunization approach for synucleinopathies: implications for Parkinson’s disease clinical trials

Markus Mandler, Elvira Valera, Edward Rockenstein, +10

Acta Neuropathologica

Neurodegenerative DiseasesAutoimmune DiseaseMedicineImmunologyClinical Trials +6

Active immunization against alpha-synuclein ameliorates the degenerative pathology and prevents demyelination in a model of multiple system atrophy

Markus Mandler, Elvira Valera, Edward Rockenstein, +10

Molecular Neurodegeneration

Galanin Receptor Subtype GalR2 Mediates Apoptosis in SH-SY5Y Neuroblastoma Cells

Alexandra Berger, Roland Lang, Kerstin Moritz, +4

Endocrinology

Gangliocytes in Neuroblastic Tumors Express Alarin, a Novel Peptide Derived by Differential Splicing of the Galanin-Like Peptide Gene

Radmila Santic, Katrin Fenninger, Kerstin Graf, +8

Journal of Molecular Neuroscience

Neuro-oncologyNovel Peptide DerivedEndocytic PathwayPathologyCell-matrix Interaction +7

Alarin is a vasoactive peptide

Radmila Santic, Sabine Schmidhuber, Roland Lang, +6

Proceedings of the National Academy of Sciences

Galanin-like PeptideImmunologyVasoactive PeptidePharmacotherapyGastrointestinal Peptide Hormone +15

Pyroglutamylated amyloid-β is associated with hyperphosphorylated tau and severity of Alzheimer’s disease

Markus Mandler, Lauren Walker, Radmila Santic, +8

Acta Neuropathologica

Neurodegenerative DiseasesAlzheimer's DiseaseMolecular NeuroscienceMedicineProteinopathies +11

Active immunization against complement factor C5a: a new therapeutic approach for Alzheimer’s disease

Christine Landlinger, Lisa Oberleitner, P. Gruber, +5

Journal of Neuroinflammation

Pharmacological and functional characterization of galanin-like peptide fragments as potent galanin receptor agonists

Roland Lang, Alexandra Berger, Radmila Santic, +4

Neuropeptides

Molecular PharmacologyGastrointestinal Peptide HormoneBiochemistryG Protein-coupled ReceptorMedicine +6

Galanin-Like Peptides Exert Potent Vasoactive Functions In Vivo

Sabine Schmidhuber, Radmila Santic, C W Tam, +3

Journal of Investigative Dermatology

MedicinePhysiologyPharmacologyCellular PhysiologyNeuropeptides

Tailoring the Antibody Response to Aggregated Aß Using Novel Alzheimer-Vaccines

Markus Mandler, Radmila Santic, P. Gruber, +7

PLoS ONE

ImmunologyAntibody ResponsePeptide ScienceNeurochemical BiomarkersAmyloid Precursor Protein +18