Alina Castell

The F-Box Protein Skp2 Participates in c-Myc Proteosomal Degradation and Acts as a Cofactor for c-Myc-Regulated Transcription

Natalie von der Lehr, Sara Johansson, Siqin Wu et al. · Molecular Cell · 2003 · 471 citations · Full text

Transcriptional Regulation, Cell Regulation, Medicine +12

A selective high affinity MYC-binding compound inhibits MYC:MAX interaction and MYC-dependent tumor cell proliferation

Alina Castell, Qinzi Yan, Karin Fawkner et al. · Scientific Reports · 2018 · 119 citations · Full text

Rv0216, a conserved hypothetical protein from <i>Mycobacterium tuberculosis</i> that is essential for bacterial survival during infection, has a double hotdog fold

Alina Castell, Patrik Johansson, Torsten Unge et al. · Protein Science · 2005 · 30 citations · Full text

The novel low molecular weight MYC antagonist MYCMI-6 inhibits proliferation and induces apoptosis in breast cancer cells

Dalal AlSultan, Emma Kavanagh, Shane O’Grady et al. · Investigational New Drugs · 2020 · 26 citations

Tumor Biology, Breast Oncology, Medicine +12

The Substrate Capture Mechanism of <i>Mycobacterium tuberculosis</i> Anthranilate Phosphoribosyltransferase Provides a Mode for Inhibition

Alina Castell, Francesca L. Short, Genevieve L. Evans et al. · Biochemistry · 2013 · 25 citations · Full text