Kosuke R. Shima

Proteasome Dysfunction Mediates Obesity-Induced Endoplasmic Reticulum Stress and Insulin Resistance in the Liver

Toshiki Otoda, Toshinari Takamura, Hirofumi Misu et al. · Diabetes · 2012 · 131 citations · Full text

Life Sciences, Biochemistry, Endocrinology +16

Clock gene expression in peripheral leucocytes of patients with type 2 diabetes

Hitoshi Ando, Toshinari Takamura, Naoto Nagata et al. · Diabetologia · 2008 · 123 citations · Full text

Life Sciences, Molecular Biology, Physiology +15

Ursodeoxycholic acid potentiates dipeptidyl peptidase-4 inhibitor sitagliptin by enhancing glucagon-like peptide-1 secretion in patients with type 2 diabetes and chronic liver disease: a pilot randomized controlled and add-on study

Kosuke R. Shima, Tsuguhito Ota, Kenichiro Kato et al. · BMJ Open Diabetes Research & Care · 2018 · 44 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +17

Rationale and design of a multicenter placebo-controlled double-blind randomized trial to evaluate the effect of empagliflozin on endothelial function: the EMBLEM trial

Atsushi Tanaka, Michio Shimabukuro, Yosuke Okada et al. · Cardiovascular Diabetology · 2017 · 32 citations · Full text

Medicine, Internal Medicine, Pharmacology +17

The hepatic circadian clock is preserved in a lipid-induced mouse model of non-alcoholic steatohepatitis

Hitoshi Ando, Toshinari Takamura, Naoto Nagata et al. · Biochemical and Biophysical Research Communications · 2009 · 27 citations · Full text

Life Sciences, Biochemistry, Physiology +16