Cyrille C. Thinnes

Molecular and cellular mechanisms of HIF prolyl hydroxylase inhibitors in clinical trials

Tzu‐Lan Yeh, T.M. Leissing, Martine I. Abboud et al. · Chemical Science · 2017 · 226 citations · Full text

Medicine, Biochemistry, Pharmacology +6

Parkinson’s disease-associated alterations of the gut microbiome predict disease-relevant changes in metabolic functions

Federico Baldini, Johannes Hertel, Estelle Sandt et al. · BMC Biology · 2020 · 223 citations · Full text

Life Sciences, Microbiology, Neuroscience +17

Integrated Analyses of Microbiome and Longitudinal Metabolome Data Reveal Microbial-Host Interactions on Sulfur Metabolism in Parkinson’s Disease

Johannes Hertel, Amy C. Harms, Almut Heinken et al. · Cell Reports · 2019 · 165 citations · Full text

Life Sciences, Biochemistry, Bioinformatics +17

5-Carboxy-8-hydroxyquinoline is a broad spectrum 2-oxoglutarate oxygenase inhibitor which causes iron translocation

Richard J. Hopkinson, Anthony Tumber, Clarence Yapp et al. · Chemical Science · 2013 · 164 citations · Full text

Life Sciences, Biochemistry, Pharmacology +7

Therapeutic targeting of oxygen-sensing prolyl hydroxylases abrogates ATF4-dependent neuronal death and improves outcomes after brain hemorrhage in several rodent models

Saravanan S. Karuppagounder, Ishraq Alim, Soah J. Khim et al. · Science Translational Medicine · 2016 · 140 citations · Full text

Medicine, Neurobiology, Neuroscience +15