Single cell RNA sequencing identifies unique inflammatory airspace macrophage subsets

Kara J. Mould, Nathan D. Jackson, Peter M. Henson, +2

JCI Insight

Acute Lung InjuryInflammatory Lung DiseaseLung InflammationImmunologySingle Cell Rna +14

Cell Origin Dictates Programming of Resident versus Recruited Macrophages during Acute Lung Injury

Kara J. Mould, Lea Barthel, Michael P. Mohning, +11

American Journal of Respiratory Cell and Molecular Biology

Acute Lung InjuryInflammatory Lung DiseaseLung InflammationResident VersusImmunology +16

Deletion of c-FLIP from CD11bhi Macrophages Prevents Development of Bleomycin-induced Lung Fibrosis

Alexandra L. McCubbrey, Lea Barthel, Michael P. Mohning, +9

American Journal of Respiratory Cell and Molecular Biology

Airspace Macrophages and Monocytes Exist in Transcriptionally Distinct Subsets in Healthy Adults

Kara J. Mould, Camille M. Moore, Shannon A. McManus, +5

American Journal of Respiratory and Critical Care Medicine

Safety and Outcomes of Prolonged Usual Care Prone Position Mechanical Ventilation to Treat Acute Coronavirus Disease 2019 Hypoxemic Respiratory Failure*

Ivor S. Douglas, C.A. Rosenthal, Diandra D. Swanson, +14

Critical Care Medicine

Polyamine import and accumulation causes immunomodulation in macrophages engulfing apoptotic cells

Alexandra L. McCubbrey, Shannon A. McManus, Jazalle McClendon, +8

Cell Reports

Activating the Nrf2-mediated antioxidant response element restores barrier function in the alveolar epithelium of HIV-1 transgenic rats

Xian Fan, Bashar S. Staitieh, J. Spencer Jensen, +5

American Journal of Physiology-Lung Cellular and Molecular Physiology

InflammationReductive StressHiv-1 Transgene ExpressionLipid PeroxidationPhysiology +10

Phagocytosis of microparticles by alveolar macrophages during acute lung injury requires MerTK

Michael P. Mohning, Stacey M. Thomas, Lea Barthel, +6

American Journal of Physiology-Lung Cellular and Molecular Physiology

Acute Lung InjuryInflammationMertk-deficient MacrophagesLung DepositionInflammatory Lung Disease +12

Single-cell RNA sequencing reveals unique monocyte-derived interstitial macrophage subsets during lipopolysaccharide-induced acute lung inflammation

Peter K. Moore, Kelsey Anderson, Shannon A. McManus, +7

American Journal of Physiology-Lung Cellular and Molecular Physiology

Inflammation-Induced Alternative Pre-mRNA Splicing in Mouse Alveolar Macrophages

William J. Janssen, Thomas Danhorn, Chelsea Harris, +6

G3 Genes Genomes Genetics