William G. Paxton

Direct stimulation of Jak/STAT pathway by the angiotensin II AT1 receptor

Mario B. Marrero, Bernhard Schieffer, William G. Paxton et al. · Nature · 1995 · 744 citations

Inflammation, Hypertension, Signal Transduction +11

Efficacy and safety of sparsentan versus irbesartan in patients with IgA nephropathy (PROTECT): 2-year results from a randomised, active-controlled, phase 3 trial

Brad H. Rovin, Jonathan Barratt, Hiddo J.L. Heerspink et al. · The Lancet · 2023 · 224 citations · Full text

Angiotensin II stimulates tyrosine phosphorylation of phospholipase C-gamma 1 in vascular smooth muscle cells.

Mario B. Marrero, William G. Paxton, Jennifer L. Duff et al. · Journal of Biological Chemistry · 1994 · 207 citations · Full text

Vascular Disease, Ang Ii, Cellular Physiology +20

Sparsentan in patients with IgA nephropathy: a prespecified interim analysis from a randomised, double-blind, active-controlled clinical trial

Hiddo J.L. Heerspink, Jai Radhakrishnan, Charles E. Alpers et al. · The Lancet · 2023 · 203 citations · Full text

Glomerulonephritis, Active-controlled Clinical Trial, Renal Function +9

Electroporation of pp60c− Antibodies Inhibits the Angiotensin II Activation of Phospholipase C-γ1 in Rat Aortic Smooth Muscle Cells

Mario B. Marrero, Bernhard Schieffer, William G. Paxton et al. · Journal of Biological Chemistry · 1995 · 176 citations · Full text