Annette Grüters

Severe early-onset obesity, adrenal insufficiency and red hair pigmentation caused by POMC mutations in humans

Heiko Krude, Heike Biebermann, W. A. P. Luck et al. · Nature Genetics · 1998 · 1.7K citations

Obesity, Metabolic Syndrome, Severe Early-onset Obesity +8

PAX8 mutations associated with congenital hypothyroidism caused by thyroid dysgenesis

Paolo Emidio Macchia, Paola Lapi, Heiko Krude et al. · Nature Genetics · 1998 · 502 citations

Developmental Biology, Genetic Disorder, Genetics +6

Proopiomelanocortin Deficiency Treated with a Melanocortin-4 Receptor Agonist

Peter Kühnen, Karine Clément, Susanna Wiegand et al. · New England Journal of Medicine · 2016 · 462 citations

Metabolic Disorder, Pharmacotherapy, Glucocorticoid +19

Consensus statement : Childhood obesity

Phyllis Speiser, Mary Rudolf, Henry Anhalt et al. · 2005 · 392 citations

Obesity Prevention, Obesity, Health Communication +16

Mutations in LHX3 result in a new syndrome revealed by combined pituitary hormone deficiency

Irène Netchine, Marie‐Laure Sobrier, Heiko Krude et al. · Nature Genetics · 2000 · 366 citations

Pituitary Gland, Endocrine Disease, Human Growth +9