Adam P. Hopkins

Identification and evaluation of a potent novel ATR inhibitor, NU6027, in breast and ovarian cancer cell lines

Amy Peasland, L-Z Wang, Emily J. Rowling et al. · British Journal of Cancer · 2011 · 192 citations · Full text

Medicine, Cancer Biology, Oncology +17

Water Networks Can Determine the Affinity of Ligand Binding to Proteins

John F. Darby, Adam P. Hopkins, Seishi Shimizu et al. · Journal of the American Chemical Society · 2019 · 155 citations

Life Sciences, Biophysics, Chemistry +17

Mode of Action and Heterologous Expression of the Natural Product Antibiotic Vancoresmycin

Bernhard Kepplinger, Stephanie Morton-Laing, Kenneth H. Seistrup et al. · ACS Chemical Biology · 2017 · 56 citations

Life Sciences, Infectious Diseases, Microbiology +17

Tripartite ATP-independent Periplasmic (TRAP) Transporters Use an Arginine-mediated Selectivity Filter for High Affinity Substrate Binding

Marcus Fischer, Adam P. Hopkins, Emmanuele Severi et al. · Journal of Biological Chemistry · 2015 · 48 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

Transport and catabolism of the sialic acids<i>N-</i>glycolylneuraminic acid and 3-keto-3-deoxy-<scp>d</scp>-glycero-<scp>d</scp>-galactonononic acid by<i>Escherichia coli</i>K-12

Adam P. Hopkins, Judith A. Hawkhead, Gavin H. Thomas · FEMS Microbiology Letters · 2013 · 34 citations · Full text

Life Sciences, Biochemistry, Microbiology +9