Human platelet-derived growth factor stimulates prostaglandin synthesis by activation and by rapid de novo synthesis of cyclooxygenase.

Andreas J. R. Habenicht, M. Goerig, J Grulich, +6

Journal of Clinical Investigation

Prostaglandin SynthesisPge2 SynthesisCell CultureCell ProliferationCell Growth +18

The LDL receptor pathway delivers arachidonic acid for eicosanoid formation in cells stimulated by platelet-derived growth factor

Andreas J. R. Habenicht, P. Salbach, M. Goerig, +5

Nature

InflammationThrombopoiesisAnti-inflammatorySignal TransductionOxysterol +10

sn-1,2-Diacylglycerols and phorbol diesters stimulate thromboxane synthesis by de novo synthesis of prostaglandin H synthase in human promyelocytic leukemia cells.

M. Goerig, Andreas J. R. Habenicht, Robert Heitz, +5

Journal of Clinical Investigation

Evidence for coordinate, selective regulation of eicosanoid synthesis in platelet-derived growth factor-stimulated 3T3 fibroblasts and in HL-60 cells induced to differentiate into macrophages or neutrophils.

M. Goerig, Andreas J. R. Habenicht, Wolfgang Zeh, +5

Journal of Biological Chemistry

Low density lipoprotein receptor-dependent prostaglandin synthesis in Swiss 3T3 cells stimulated by platelet-derived growth factor.

Andreas J. R. Habenicht, H. A. Dresel, M. Goerig, +5

Proceedings of the National Academy of Sciences

Low DensityOxidative StressInflammationMetabolic SyndromeReceptor-dependent Prostaglandin Synthesis +21

Release of prostanoids into the portal and hepatic vein in patients with chronic liver disease

H. Wernze, W Tittor, M. Goerig

Hepatology

Cell cycle-dependent changes in arachidonic acid and glycerol metabolism in Swiss 3T3 cells stimulated by platelet-derived growth factor.

Andreas J. R. Habenicht, John A. Glomset, M. Goerig, +4

Journal of Biological Chemistry

Ibuprofen as an over-the-counter drug: is there a risk for renal injury?

Johannes F.E. Mann, M. Goerig, Kay Brune, +1

PubMed

Drug SafetyUrologyRenal FunctionMedicineKidney Failure +10

PROSTANOID RELEASE IN EXPERIMENTAL LIVER TRANSPLANTATION

S. Post, M. Goerig, Gerhard Otto, +4

Transplantation

ImmunologyOrgan PreservationLiver GraftingInflammationHepatotoxicity +16

Early reversible induction of leukotriene synthesis in chicken myelomonocytic cells transformed by a temperature-sensitive mutant of avian leukemia virus E26.

Andreas J. R. Habenicht, M. Goerig, D. Rothe, +4

Proceedings of the National Academy of Sciences

Reversible InductionSynthetic VirologyImmunologyImmunologic MechanismCell Culture +16