Daniel Lai

The clonal and mutational evolution spectrum of primary triple-negative breast cancers

Sohrab P. Shah, Andrew Roth, Rodrigo Goya et al. · Nature · 2012 · 2K citations

Breast Oncology, Tumor Heterogeneity, Medicine +10

CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours

Hong Xu, Marco Di Antonio, Steven McKinney et al. · Nature Communications · 2017 · 573 citations · Full text

Probabilistic cell-type assignment of single-cell RNA-seq for tumor microenvironment profiling

Allen W. Zhang, Ciara H. O’Flanagan, Elizabeth A. Chavez et al. · Nature Methods · 2019 · 407 citations · Full text

Functional Genomics, Tumor Heterogeneity, Medicine +11

Interfaces of Malignant and Immunologic Clonal Dynamics in Ovarian Cancer

Allen W. Zhang, Andrew McPherson, Katy Milne et al. · Cell · 2018 · 373 citations

Malignant Disease, Tumor Heterogeneity, Medicine +9

Molecular and Genetic Characterization of MHC Deficiency Identifies EZH2 as Therapeutic Target for Enhancing Immune Recognition

Daisuke Ennishi, Katsuyoshi Takata, Wendy Béguelin et al. · Cancer Discovery · 2019 · 301 citations