Shin Hisahara

Safety and efficacy of eculizumab in anti-acetylcholine receptor antibody-positive refractory generalised myasthenia gravis (REGAIN): a phase 3, randomised, double-blind, placebo-controlled, multicentre study

James F. Howard, Kimiaki Utsugisawa, Michael Benatar et al. · The Lancet Neurology · 2017 · 800 citations

Medicine, Pharmacology, Pharmacotherapy +6

Safety, efficacy, and tolerability of efgartigimod in patients with generalised myasthenia gravis (ADAPT): a multicentre, randomised, placebo-controlled, phase 3 trial

James F. Howard, Vera Bril, Tuan Vu et al. · The Lancet Neurology · 2021 · 668 citations · Full text

Medicine, Endocrinology, Pharmacotherapy +4

Induction of Manganese Superoxide Dismutase by Nuclear Translocation and Activation of SIRT1 Promotes Cell Survival in Chronic Heart Failure

Masaya Tanno, Atsushi Kuno, Toshiyuki Yano et al. · Journal of Biological Chemistry · 2010 · 354 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

Histone deacetylase SIRT1 modulates neuronal differentiation by its nuclear translocation

Shin Hisahara, Susumu Chiba, Hiroyuki Matsumoto et al. · Proceedings of the National Academy of Sciences · 2008 · 284 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +17

ICE/CED‐3 Family Executes Oligodendrocyte Apoptosis by Tumor Necrosis Factor

Shin Hisahara, Shin’ichi Shoji, Hideyuki Okano et al. · Journal of Neurochemistry · 1997 · 141 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17