Elaine O’Loughlin

The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases

Susanne Krasemann, Charlotte Madore, Ron Cialic et al. · Immunity · 2017 · 2.8K citations · Full text

Neurodegenerative Diseases, Alzheimer's Disease, Medicine +12

Acute in utero exposure to lipopolysaccharide induces inflammation in the pre- and postnatal brain and alters the glial cytoarchitecture in the developing amygdala

Elaine O’Loughlin, Janelle M.P. Pakan, Deniz Yilmazer‐Hanke et al. · Journal of Neuroinflammation · 2017 · 122 citations · Full text

Interdependent and independent roles of type I interferons and IL-6 in innate immune, neuroinflammatory and sickness behaviour responses to systemic poly I:C

Carol Murray, Éadaoin W. Griffin, Elaine O’Loughlin et al. · Brain Behavior and Immunity · 2015 · 93 citations · Full text

The brain parenchyma has a type I interferon response that can limit virus spread

Eugene Drokhlyansky, Didem Göz Aytürk, Timothy K. Soh et al. · Proceedings of the National Academy of Sciences · 2016 · 54 citations · Full text

Human Alzheimer’s disease gene expression signatures and immune profile in APP mouse models: a discrete transcriptomic view of Aβ plaque pathology

Sarah M. Rothman, Keith Q. Tanis, Pallavi Gandhi et al. · Journal of Neuroinflammation · 2018 · 41 citations · Full text