ARG1-expressing microglia show a distinct molecular signature and modulate postnatal development and function of the mouse brain

Vassilis Stratoulias, Rocío Ruiz, Shigeaki Kanatani, +29

Nature Neuroscience

mTOR-dependent translation amplifies microglia priming in aging mice

Lily Keane, Ignazio Antignano, Sean‐Patrick Riechers, +17

Journal of Clinical Investigation

The DNA methyltransferase DNMT3A contributes to autophagy long-term memory

Patricia González-Rodríguez, Mathilde Cheray, Jens Füllgrabe, +10

Autophagy

Inhibition of microglial EZH2 leads to anti-tumoral effects in pediatric diffuse midline gliomas

Lily Keane, Mathilde Cheray, Dalel Saidi, +6

Neuro-Oncology Advances

ULK3-dependent activation of GLI1 promotes DNMT3A expression upon autophagy induction

Patricia González-Rodríguez, Mathilde Cheray, Lily Keane, +2

Autophagy

SETD2 transcriptional control of ATG14L/S isoforms regulates autophagosome–lysosome fusion

Patricia González-Rodríguez, Elizabeth Delorme‐Axford, Amélie Bernard, +7

Cell Death and Disease

Atg7 deficiency in microglia drives an altered transcriptomic profile associated with an impaired neuroinflammatory response

Mathilde Cheray, Lily Keane, Kathleen Grabert, +1

Molecular Brain

Proteome integral solubility alteration high-throughput proteomics assay identifies Collectin-12 as a non-apoptotic microglial caspase-3 substrate

Kathleen Grabert, Pinelopi Engskog‐Vlachos, Martin Škandík, +6

Cell Death and Disease

Age-associated microglial transcriptome leads to diminished immunogenicity and dysregulation of MCT4 and P2RY12/P2RY13 related functions

Martin Škandík, Guillermo Vázquez-Cabrera, Lily Keane, +6

Cell Death Discovery