David C. Boyles

Fit-for-Purpose Development of the Enabling Route to Crizotinib (PF-02341066)

Pieter D. de Koning, Douglas McAndrew, Robert Moore et al. · Organic Process Research & Development · 2011 · 89 citations

Medicinal Chemistry, Boronate 8, Bioorganic Chemistry +14

Kiloscale Buchwald–Hartwig Amination: Optimized Coupling of Base-Sensitive 6-Bromoisoquinoline-1-carbonitrile with (<i>S</i>)-3-Amino-2-methylpropan-1-ol

Jeffrey B. Sperry, Kristin E. Price Wiglesworth, Ian D. Edmonds et al. · Organic Process Research & Development · 2014 · 45 citations

Combinatorial Chemistry, Bioorganic Chemistry, Engineering +17

Electrophilic <i>N</i>-Amination of Two Quinazoline-2,4-diones Using Substituted (Nitrophenyl)hydroxylamines

David C. Boyles, Timothy T. Curran, Parlett et al. · Organic Process Research & Development · 2002 · 33 citations

Highest Onset Temperature, Engineering, Best Yield +7

The Preparation of Two, Preclinical Amino-quinazolinediones as Antibacterial Agents

V. G. BEYLIN, David C. Boyles, Timothy T. Curran et al. · Organic Process Research & Development · 2007 · 31 citations

Preclinical Amino-quinazolinediones, Bioorganic Chemistry, Organic Chemistry +19

Development of a practical synthesis of novel, pyrrole-based HMG-CoA reductase inhibitors

Jeffrey A. Pfefferkorn, Daniel M. Bowles, William S. Kissel et al. · Tetrahedron · 2007 · 29 citations

Medicinal Chemistry, Practical Synthesis, Aldo-keto Reductase +9