Chihiro Kezuka

Acquisition of doxorubicin resistance facilitates migrating and invasive potentials of gastric cancer MKN45 cells through up-regulating aldo–keto reductase 1B10

Yoshifumi Morikawa, Chihiro Kezuka, Satoshi Endo et al. · Chemico-Biological Interactions · 2015 · 45 citations

Tumor Biology, Oncology, Doxorubicin Resistance +11

Aldo-keto reductase 1B10 promotes development of cisplatin resistance in gastrointestinal cancer cells through down-regulating peroxisome proliferator-activated receptor-γ-dependent mechanism

Toshiyuki Matsunaga, Ayaka Suzuki, Chihiro Kezuka et al. · Chemico-Biological Interactions · 2016 · 38 citations

Cisplatin Resistance, Aldo-keto Reductase 1B10, Oncology +9

Induction of aldo-keto reductases (AKR1C1 and AKR1C3) abolishes the efficacy of daunorubicin chemotherapy for leukemic U937 cells

Toshiyuki Matsunaga, Ayano Yamaguchi, Yoshifumi Morikawa et al. · Anti-Cancer Drugs · 2014 · 36 citations

Aldo-keto Reductase, Chemoprevention Strategy, Cell Differentiation +18

Pathophysiological roles of autophagy and aldo-keto reductases in development of doxorubicin resistance in gastrointestinal cancer cells

Toshiyuki Matsunaga, Saori Kawabata, Yuji Yanagihara et al. · Chemico-Biological Interactions · 2019 · 28 citations

Aldo-keto Reductases, Cell Autophagy, Doxorubicin Resistance +10

Up-Regulation of Carbonyl Reductase 1 Renders Development of Doxorubicin Resistance in Human Gastrointestinal Cancers

Toshiyuki Matsunaga, Chihiro Kezuka, Yoshifumi Morikawa et al. · Biological and Pharmaceutical Bulletin · 2015 · 25 citations · Full text

Doxorubicin Resistance, Human Gastrointestinal Cancers, Gastrointestinal Oncology +14