Phosphatidylinositol 3-Kinase-, Actin-, and Microtubule-Dependent Transport of Semliki Forest Virus Replication Complexes from the Plasma Membrane to Modified Lysosomes

Pirjo Spuul, Giuseppe Balistreri, Leevi Kääriäinen, +1

Journal of Virology

Viral ReplicationMolecular BiologyCytoskeletonModified LysosomesVirus Structure +16

Role of the Amphipathic Peptide of Semliki Forest Virus Replicase Protein nsP1 in Membrane Association and Virus Replication

Pirjo Spuul, Anne Salonen, Andres Merits, +3

Journal of Virology

Assembly of Alphavirus Replication Complexes from RNA and Protein Components in a Novel <i>trans</i> -Replication System in Mammalian Cells

Pirjo Spuul, Giuseppe Balistreri, Kirsi Hellström, +3

Journal of Virology

Viral ReplicationViral Polymerase StructureViral Polymerase MechanismMolecular BiologyViral Structural Protein +16

Template RNA Length Determines the Size of Replication Complex Spherules for Semliki Forest Virus

Katri Kallio, Kirsi Hellström, Giuseppe Balistreri, +3

Journal of Virology

Early secretory pathway localization and lack of processing for hepatitis E virus replication protein pORF1

Julia Perttilä, Pirjo Spuul, Tero Ahola

Journal of General Virology

VEGF-A/Notch-Induced Podosomes Proteolyse Basement Membrane Collagen-IV during Retinal Sprouting Angiogenesis

Pirjo Spuul, Thomas Daubon, Bettina Pitter, +5

Cell Reports

Mutations at the palmitoylation site of non-structural protein nsP1 of Semliki Forest virus attenuate virus replication and cause accumulation of compensatory mutations

Eva Žusinaite, Kairit Tints, Kaja Kiiver, +4

Journal of General Virology

Virus ViabilityViral ReplicationGeneticsMolecular BiologyMolecular Genetics +15

Nonlinear machine learning pattern recognition and bacteria-metabolite multilayer network analysis of perturbed gastric microbiome

Claudio Durán, Sara Ciucci, Alessandra Palladini, +15

Nature Communications

ALK5 and ALK1 Play Antagonistic Roles in Transforming Growth Factor β-Induced Podosome Formation in Aortic Endothelial Cells

Filipa Curado, Pirjo Spuul, Isabel Egaña, +7

Molecular and Cellular Biology

Tgf-β-specific ResponseImmune RegulationCellular PhysiologyAlk1 Tgf-β ReceptorAngiogenesis +15

VEGF-A stimulates podosome-mediated collagen-IV proteolysis in microvascular endothelial cells

Thomas Daubon, Pirjo Spuul, Florian Alonso, +2

Journal of Cell Science