Leslie D. Alexander

Design and synthesis of Hsp90 inhibitors: Exploring the SAR of Sansalvamide A derivatives

Robert P. Sellers, Leslie D. Alexander, Victoria A. Johnson et al. · Bioorganic & Medicinal Chemistry · 2010 · 79 citations · Full text

Sansalvamide A Derivatives, Medicinal Chemistry, Pharmaceutical Science +12

Synthesis of sansalvamide A peptidomimetics: triazole, oxazole, thiazole, and pseudoproline containing compounds

Melinda R. Davis, Erinprit K. Singh, Hendra Wahyudi et al. · Tetrahedron · 2011 · 75 citations · Full text

Derivative (Chemistry), Pseudoproline Containing Compounds, Medicine +8

Macrocycles That Inhibit the Binding between Heat Shock Protein 90 and TPR-Containing Proteins

Veronica C. Ardi, Leslie D. Alexander, Victoria A. Johnson et al. · ACS Chemical Biology · 2011 · 70 citations · Full text

Tpr-containing Proteins, Protein Assembly, Molecular Biology +19

Synthesis and evaluation of biotinylated sansalvamide A analogs and their modulation of Hsp90

Joseph B. Kunicki, Mark N. Petersen, Leslie D. Alexander et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 37 citations · Full text

Medicinal Chemistry, Biochemistry, Natural Sciences +5

Evaluation of Di-Sansalvamide A Derivatives: Synthesis, Structure−Activity Relationship, and Mechanism of Action

Leslie D. Alexander, Robert P. Sellers, Melinda R. Davis et al. · Journal of Medicinal Chemistry · 2009 · 22 citations · Full text

Engineering, Organic Chemistry, Di-sansalvamide A Derivatives +20