Thorben Mährle

T cell receptor next-generation sequencing reveals cancer-associated repertoire metrics and reconstitution after chemotherapy in patients with hematological and solid tumors

Donjetë Simnica, Nuray Akyüz, Simon Schliffke et al. · OncoImmunology · 2019 · 68 citations · Full text

Medicine, Immunology, Oncology +15

T-cell diversification reflects antigen selection in the blood of patients on immune checkpoint inhibition and may be exploited as liquid biopsy biomarker

Nuray Akyüz, Anna Brandt, Alexander Stein et al. · International Journal of Cancer · 2016 · 50 citations · Full text

Life Sciences, Immunology, Oncology +17

Deep sequencing of bone marrow microenvironments of patients with del(5q) myelodysplastic syndrome reveals imprints of antigenic selection as well as generation of novel T-cell clusters as a response pattern to lenalidomide

Thorben Mährle, Nuray Akyüz, Pim Fuchs et al. · Haematologica · 2019 · 11 citations · Full text

Life Sciences, Hematology, Immunology +17