Tilman Läppchen

Diels–Alder Reaction for Tumor Pretargeting: In Vivo Chemistry Can Boost Tumor Radiation Dose Compared with Directly Labeled Antibody

Raffaella Rossin, Tilman Läppchen, Sandra M. van den Bosch et al. · Journal of Nuclear Medicine · 2013 · 178 citations · Full text

<i>Trans</i>-Cyclooctene Tag with Improved Properties for Tumor Pretargeting with the Diels–Alder Reaction

Raffaella Rossin, Sander M. J. van Duijnhoven, Tilman Läppchen et al. · Molecular Pharmaceutics · 2014 · 109 citations

Improved Properties, Engineering, Immunology +20

Probing FtsZ and Tubulin with C8-Substituted GTP Analogs Reveals Differences in Their Nucleotide Binding Sites

Tilman Läppchen, Victorine A. Pinas, Aloysius F. Hartog et al. · Chemistry & Biology · 2008 · 80 citations · Full text

Protein Chemistry, Protein Function, Protein Assembly +6

GTP Analogue Inhibits Polymerization and GTPase Activity of the Bacterial Protein FtsZ without Affecting Its Eukaryotic Homologue Tubulin

Tilman Läppchen, Aloysius F. Hartog, Victorine A. Pinas et al. · Biochemistry · 2005 · 77 citations

DOTA-tetrazine probes with modified linkers for tumor pretargeting

Tilman Läppchen, Raffaella Rossin, Tiemen van Mourik et al. · Nuclear Medicine and Biology · 2017 · 47 citations · Full text

Engineering, Theranostics, Tumor Targeting +5